Results 301 to 310 of about 360,977 (393)

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Diagnostic and Therapeutic Challenges in a Case of Achalasia Masquerading as Gastroesophageal Reflux Disease (GERD). [PDF]

Cureus
Nanduri RS, Gurram A, Karnath N, Karnath B.   +3 more
europepmc   +1 more source

Ultrafast Nonlinear Dynamics of Indium Tin Oxide Nanocrystals Probed via Fieldoscopy

Advanced Science, EarlyView.
The ultrafast nonlinear dynamics of indium tin oxide nanocrystals excited with 1 MHz, 10 fs pulses, at their localized surface plasmon frequency, and near their epsilon‐near‐zero wavelength is probed via fieldoscopy. The study demonstrates fluence‐dependent switching behavior, advancing the understanding of high‐speed optical modulation in plasmonic ...
Andreas Herbst, Anchit Srivastava, Kilian Scheffter, Soyeon Jun, Steffen Gommel, Luca Rebecchi, Sidharth Kuriyil, Andrea Rubino, Nicolò Petrini, Ilka Kriegel, Hanieh Fattahi   +10 more
wiley   +1 more source

Structure-Function Interplay in Piezoelectric PCL/BaTiO₃ Scaffolds Fabricated by Phase Separation: Correlation of Morphology, Mechanics, and Cytocompatibility. [PDF]

Int J Mol Sci
Alotaibi A, Desai Y, Miszuk J, Choi JH, Michalakis K, Tsouknidas A.   +5 more
europepmc   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source

Congenital Sliding Hiatal Hernia in a 5-Week-Old Ex-Preterm Infant With Recurrent Gastroesophageal Reflux Amid the COVID-19 Pandemic. [PDF]

Clin Case Rep
Chap C, Bin V, Bin S.
europepmc   +1 more source

Esophageal retention on modified barium swallow study: Limited predictive value for true esophageal pathology. [PDF]

World J Gastrointest Pathophysiol
Chen SL, Partida D, Wang C, Kathpalia P.
europepmc   +1 more source

Side-on Coordination in Fluorido Difluoroamido Complexes FMNF₂ of Heavy Alkaline Earth Metals (M = Ca, Sr, Ba). [PDF]

Chemistry
Xia X, Medel R, Riedel S.
europepmc   +1 more source

Pneumatic versus liquid enema reduction in the management of pediatric intussusception: an updated systematic review and meta-analysis. [PDF]

Ann Med Surg (Lond)
Qafesha RM, Sharabati I, Kashbour M, Elbadry M, Eldeeb H, Ayesh BM, Elganady A, Abdelgalil MS, Abdulrazzak M, Jobran AWM.   +9 more
europepmc   +1 more source