The Open Reading Frame 7b of the SARS-CoV-2 Disperse Trans-Golgi and Activate the NLRP3 Inflammasome. [PDF]
ABSTRACT Inflammasomes orchestrate the inflammatory response against bacterial and viral infections, thereby initiating the synthesis of pro‐inflammatory cytokines, mainly IL‐1β and IL‐18. SARS‐CoV‐2 infection induces an inflammatory response mediated by the activation of NLRP1 and NLRP3 inflammasomes.
García-Villalba J +4 more
europepmc +2 more sources
Efficacy of a Multicomponent Intervention for Frailty or Physical Function in Prefrail or Frail Older Adults: FRAILMERIT Multicenter Clinical Trial. [PDF]
Clinical management of the older adult. ABSTRACT Objectives Frailty is a common condition in community‐dwelling older adults with high health and socioeconomic implications. However, primary care‐led randomized trials have been scarcely tested. Design Multicenter cluster randomized clinical trial.
Abizanda Saro A +23 more
europepmc +2 more sources
The Highly Conserved Cys95 Residue of Fructose-1,6-Bisphosphatase 1 Mediates the pH-Driven Structure and Activity of the Enzyme and Photosynthesis. [PDF]
ABSTRACT In Arabidopsis, exposure to microbial volatile compounds promotes thiol reduction of the Cys95 residue of the photosynthetic enzyme fructose‐1,6‐bisphosphatase (cFBP1). Although highly conserved in plants, the Cys95 function still remains unknown. We characterised recombinant wild‐type (WT) cFBP1 and a variant (C95S) in which the Cys95 residue
Gámez-Arcas S +9 more
europepmc +2 more sources
Numbers on the Visigothic Slates: A Cognitive Approach. [PDF]
Abstract Numerical notation found on multiple slates from Early Medieval Visigothic Iberia remains undeciphered. Previous studies have proposed that they simply represent Roman numerals. However, the comparative study of the numbers on the written and numerical slates suggests that they do not in fact represent the same graphic code.
Fernández Cadenas N.
europepmc +2 more sources
Vicente Blasco Ibáñez, Pío Baroja y el comercio del libro en los Estados Unidos
Tanto Vicente Blasco Ibáñez como Pío Baroja fueron ampliamente publicados en los Estados Unidos y disfrutaron de una relación profesional y personal con sus editores.
Fernando Ariza González
doaj +1 more source
Itinerario de la novela modernista española
Este artículo ofrece una panorámica de la novela española del periodo modernista y trata de explicar los modos en que algunas obras españolas de esa época reflejan los principales elementos de la novela modernista europea.
Juan Antonio Garrido Ardila
doaj +1 more source
This article analyses the incidents that Baroja suffered during the afternoon and evening of 22 July 1936. Personal testimonies of the author and his family and analysis made by some biographer's are reexamined using unpublished documents.
Fernando Mikelarena Peña
doaj +1 more source
Anterior Scleral Thickness Profile in Keratoconus
Purpose: Considering that peripheral corneal thinning occurs in keratoconus (KC), the anterior scleral thickness (AST) profile was measured to compare thickness variations in healthy and KC eyes across several meridians.
Neus Burguera-Giménez +3 more
doaj +1 more source
Demófilo, Folklore and Contemporary Spanish Anthropology. Readings of Antonio Machado y Álvarez (1846–1893) [PDF]
Antonio Machado y Álvarez (1846–1893), also known as Demófilo, was a pioneering collector and interpreter of folkloristic material from Andalusia and Spain.
Pfeilstetter, Richard
core +1 more source
Levinas’ notion of neighbor as an approach to understand Pío Baroja, otherness and modern Spain. [PDF]
The Cold War era touched Spain only subtly. Because of the geopolitical situation of Europe during the second half of the 20th century, Spain remained almost isolated from macro politics, attempting impossible alliances with Italian and German fascism ...
Arranz, Iker
core

