Barrett esophagus is a metaplastic change in the lining of the distal esophageal epithelium, characterized by replacement of the normal squamous epithelium by specialized intestinal metaplasia. The presence of Barrett esophagus increases the risk of esophageal adenocarcinoma several-fold.
Prasad G. Iyer, Vivek Kaul
openaire +2 more sources
The Oxidative Damage and Inflammation Mechanisms in GERD-Induced Barrett’s Esophagus
Barrett’s esophagus is a major complication of gastro-esophageal reflux disease and an important precursor lesion for the development of Barrett’s metaplasia and esophageal adenocarcinoma.
Deqiang Han, Deqiang Han, Chao Zhang
doaj +1 more source
Circulating Serum Exosomal miRNAs As Potential Biomarkers for Esophageal Adenocarcinoma [PDF]
Author version made available in accordance with publisher policy.Abstract Background The poor prognosis and rising incidence of esophageal adenocarcinoma highlight the need for improved detection methods.
Bowen, Joanne M +12 more
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DINAMIC SCREENING OF PRECANCEROUS ESOPHAGUS USING MOLECULAR GENETIC ANALYSIS
Introduction. Esophageal adenocarcinoma develops from areas of intestinal metaplasia in Barrett’s esophagus, similar to how intestinal metaplasia transforms into gastric adenocarcinomas in the stomach.
V. V. Anishchenko +5 more
doaj +1 more source
Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. [PDF]
Barrett's esophagus is a premalignant condition whereby the normal stratified squamous esophageal epithelium undergoes a transdifferentiation program resulting in a simple columnar epithelium reminiscent of the small intestine.
Douglas B Stairs +7 more
doaj +1 more source
Structural markers observed with endoscopic 3-dimensional optical coherence tomography correlating with Barrett's esophagus radiofrequency ablation treatment response [PDF]
Background Radiofrequency ablation (RFA) is effective for treating Barrett's esophagus (BE) but often involves multiple endoscopy sessions over several months to achieve complete response.
Adler, Desmond C. +11 more
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Barrett’s esophagus (BE) is caused by metaplasia of squamous epithelium into columnar epithelium, mainly in the lower esophagus. Updates have been made in the etiology, diagnosis and treatment of BE since its first report as an ulcerative lesion in the ...
Yong Kang Lee
doaj +1 more source
Reduced risk of Barrett’s esophagus in statin users: case–control study and meta-analysis [PDF]
Background: Use of statins has been associated with a reduced incidence of esophageal adenocarcinoma in population-based studies. However there are few studies examining statin use and the development of Barrett’s esophagus.
A Dubecz +47 more
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LOW PREVALENCE OF BARRETT’S ESOPHAGUS IN A RISK AREA FOR ESOPHAGEAL CANCER IN SOUTH OF BRAZIL
BACKGROUND: Barrett’s esophagus a complication of gastroesophageal reflux disease (GERD) is a precursor of esophageal adenocarcinoma. The incidence of esophageal adenocarcinoma has been increasing in most Western countries.
Diego Michelon DE CARLI +2 more
doaj +1 more source
Smartphone microendoscopy for high resolution fluorescence imaging [PDF]
High resolution optical endoscopes are increasingly used in diagnosis of various medical conditions of internal organs, such as the gastrointestinal tracts, but they are too expensive for use in resource-poor settings. On the other hand, smartphones with
Hong, Xiangqian +3 more
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