Results 31 to 40 of about 463,247 (329)

Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis. [PDF]

PLoS Genetics, 2011
Although a combination of genomic and epigenetic alterations are implicated in the multistep transformation of normal squamous esophageal epithelium to Barrett esophagus, dysplasia, and adenocarcinoma, the combinatorial effect of these changes is unknown.
Hector Alvarez, Joanna Opalinska, Li Zhou, Davendra Sohal, Melissa J Fazzari, Yiting Yu, Christina Montagna, Elizabeth A Montgomery, Marcia Canto, Kerry B Dunbar, Jean Wang, Juan Carlos Roa, Yongkai Mo, Tushar Bhagat, K H Ramesh, Linda Cannizzaro, J Mollenhauer, Reid F Thompson, Masako Suzuki, Stephen J Meltzer, Ari Melnick, John M Greally, Anirban Maitra, Amit Verma   +23 more
doaj   +1 more source

Attention-Based Deep Neural Networks for Detection of Cancerous and Precancerous Esophagus Tissue on Histopathological Slides [PDF]

JAMA Netw Open. 2019;2(11):e1914645, 2018
Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown promising results. These approaches, however, require a laborious annotation process and are fragmented.
arxiv   +1 more source

Origin of adenocarcinoma in Barrett's esophagus: P53 and Ki67 expression and histopathologic background Origem do adenocarcinoma no esôfago de Barrett: bases histopathológicas e expressão dos genes p53 e Ki67

Clinics, 2005
Barrett's esophagus is the substitution of squamous epithelium of the distal esophagus by columnar epithelium. Intestinal metaplasia in Barrett's esophagus is considered to be the main risk factor for the development of adenocarcinoma.
Sergio Szachnowicz, Ivan Cecconello, Kiyoshi Iriya, Allan Garms Marson, Flávio Roberto Takeda, Joaquim José Gama-Rodrigues   +5 more
doaj   +1 more source

Prevalence of Barrett's esophagus in individuals without typical symptoms of gastroesophageal reflux disease Prevalência do esôfago de Barrett em indivíduos sem sintomas típicos da doença por refluxo gastroesofágico

Arquivos de Gastroenterologia, 2008
BACKGROUND: Barrett’s esophagus, the major risk factor for esophageal adenocarcinoma, is detected in approximately 10%-14% of individuals submitted to upper endoscopy for the assessment of gastroesophageal reflux disease related symptoms.
Mauro Carneiro de Freitas, Luciana Dias Moretzsohn, Luiz G. V. Coelho   +2 more
doaj   +1 more source

Os nitritos são importantes na gênese do adenocarcinoma associado ao esôfago de Barrett? Are the nitrites important in a genesis of the adenocarcinoma associated to the Barrett esophagus?

ABCD: Arquivos Brasileiros de Cirurgia Digestiva, 2008
RACIONAL: O esôfago de Barrett é complicação do refluxo gastroesofágico e predispõe ao surgimento do adenocarcinoma, sendo que vários fatores têm sido relacionados à sua etiopatogenia.
Sergio Ferreira Módena, Luciana Rodrigues Meirelles, Marina Rachel Araújo   +2 more
doaj   +1 more source

Geometry-Aware Latent Representation Learning for Modeling Disease Progression of Barrett's Esophagus [PDF]

arXiv, 2023
Barrett's Esophagus (BE) is the only precursor known to Esophageal Adenocarcinoma (EAC), a type of esophageal cancer with poor prognosis upon diagnosis. Therefore, diagnosing BE is crucial in preventing and treating esophageal cancer. While supervised machine learning supports BE diagnosis, high interobserver variability in histopathological training ...
arxiv  

Endoscopic therapy for Barrett′s esophagus

Journal of Digestive Endoscopy, 2012
Barrett’s esophagus (BE) is the precursor lesion to esophageal adenocarcinoma. This cancer has undergone a rapid increase in incidence in Western societies in the last 30 years.
Nicholas J. Shaheen
doaj   +1 more source

Large Language Models for Granularized Barrett's Esophagus Diagnosis Classification [PDF]

arXiv, 2023
Diagnostic codes for Barrett's esophagus (BE), a precursor to esophageal cancer, lack granularity and precision for many research or clinical use cases. Laborious manual chart review is required to extract key diagnostic phenotypes from BE pathology reports. We developed a generalizable transformer-based method to automate data extraction.
arxiv  

Immunoreactivity of cytokeratins 7 and 20 in goblet cells and columnar blue cells in patients with endoscopic evidence of Barrett's esophagus Imunoreatividade das citoqueratinas 7 e 20 nas células caliciformes e células colunares azuis em pacientes com evidência endoscópica de esôfago de Barrett

Arquivos de Gastroenterologia, 2009
CONTEXT: Barrett's esophagus is characterized by the presence of goblet cells. However, when alcian-blue is utilized, another type of cells, called columnar blue cells, is frequently present in the distal esophagus of patients with endoscopic evidence of
João Carlos Cantarelli Jr., Renato Borges Fagundes, Luise Meurer, Marta Pires da Rocha, André Nicola, Cleber Dario Pinto Kruel   +5 more
doaj   +1 more source

Recurrence of intestinal metaplasia and early neoplasia after endoscopic eradication therapy for Barrett’s esophagus: A systematic review and meta-analysis [PDF]

, 2017
Background Conflicting data exist with regard to recurrence rates of intestinal metaplasia (IM) and dysplasia after achieving complete eradication of intestinal metaplasia (CE-IM) in Barrett’s esophagus (BE) patients.
Cinnor, Birtukan, Das, Ananya, Early, Dayna S, Edmundowicz, Steven A, Fujii-Lau, Larissa L, Gaddam, Srinivas, Komanduri, Srinadh, Kushnir, Vladimir, Mullady, Daniel, Muthusamy, V. Raman, Shaheen, Nicholas, Simon, Violette C, Wani, Sachin, Wilson, Robert   +13 more
core   +2 more sources