Results 81 to 90 of about 15,494 (292)

Management of Barrett's Esophagus [PDF]

open access: yesMayo Clinic Proceedings, 1998
In Barrett's esophagus, the squamous lining of the lower esophagus is replaced by columnar epithelium. Barrett's esophagus is associated with gastroesophageal reflux and an increased risk of the development of esophageal cancer. Endoscopy shows red columnar epithelium in the lower esophagus. Biopsy is needed to confirm intestinal metaplasia. Some cases
openaire   +3 more sources

The Milan Score Predicts Objective Gastroesophageal Reflux Disease in Patients With Type 2 Esophagogastric Junction

open access: yesNeurogastroenterology &Motility, EarlyView.
The novel manometric parameter Milan Score could be useful in predicting which patients with type 2 EGJ have a high likelihood of objective GERD, therefore discriminating which patients may need escalation of GERD investigation and management. ABSTRACT Introduction High‐resolution manometry (HRM) allows assessment of esophagogastric junction (EGJ ...
Davide Ferrari   +29 more
wiley   +1 more source

EXPRESSION OF ENDOPLASMIC RETICULUM OXIDOREDUCTASES (EROS) AND THEIR ROLE IN THE GI TRACT [PDF]

open access: yes, 2012
It has been shown that some ER redox enzymes are differentially expressed in stomach and oesophagus tissue. The tissues of the gastrointestinal system, which are subject to external changes of environment during the process of digestion, represent a ...
WATSON, GRAEME
core  

Molecular biomarkers and ablative therapies for Barrett’s esophagus [PDF]

open access: yes, 2012
Author version made available in accordance with the publisher's policy.Barrett’s esophagus is the major risk factor for esophageal adenocarcinoma. Endoscopic interventions which ablate Barrett’s esophagus mucosa lead to replacement with a new squamous ...
Chisolm, Jacob A   +3 more
core   +1 more source

The Milan Score is an Effective Manometric Tool to Predict Gastroesophageal Reflux in Patients With Laryngopharyngeal Symptoms

open access: yesNeurogastroenterology &Motility, EarlyView.
Patients with isolated LPS demonstrated a lower likelihood of EGJ disruption, pathologic GERD, and abnormal Milan score. The Milan score performed similarly well in the identification of GERD in both LPS and typical symptoms. The Milan score could therefore be used as an upfront test in LPS patients.
Stefano Siboni   +26 more
wiley   +1 more source

Confocal laser endomicroscopy for diagnosis of Barrett´s esophagus

open access: yesFrontiers in Oncology, 2012
Barrett´s esophagus (BE) is established as a premalignant condition in the distal esophagus. Current surveillance guidelines recommend random biopsies every 1-2 cm at intervals of 3-5 years.
Helmut eNeumann   +3 more
doaj   +1 more source

A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease

open access: yesNeurogastroenterology &Motility, EarlyView.
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech   +4 more
wiley   +1 more source

An investigation of the progression from Barrett's esophagus to adenocarcinoma [PDF]

open access: yes, 2016
Barrett's esophagus is a metaplasia of the epithelium of the lower esophagus from a normal squamous appearance to a columnar appearance more typically found in the stomach. It is normally caused by prolonged gastric reflux. While Barrett's esophagus is
Palmese, Scott Joseph
core   +1 more source

Assessment of Esophagogastric Junction Barrier Function With the Supine‐Upright Transition of the Chicago Classification Protocol

open access: yesNeurogastroenterology &Motility, EarlyView.
ABSTRACT Background & Aims The straight leg raise (SLR) is a provocative maneuver used to assess the esophagogastric junction (EGJ) barrier function during high‐resolution manometry (HRM) and is part of the Milan Score (MS). The Chicago Classification 4.0 (CCv4.0) protocol requires patients to perform a supine‐upright transition (SUT), increasing intra‐
Stefano Siboni   +17 more
wiley   +1 more source

MiRNA-Related SNPs and Risk of Esophageal Adenocarcinoma and Barrett's Esophagus: Post Genome-Wide Association Analysis in the BEACON Consortium. [PDF]

open access: yes, 2015
Incidence of esophageal adenocarcinoma (EA) has increased substantially in recent decades. Multiple risk factors have been identified for EA and its precursor, Barrett's esophagus (BE), such as reflux, European ancestry, male sex, obesity, and tobacco ...
Bernstein, Leslie   +20 more
core   +7 more sources

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