Results 81 to 90 of about 1,829,399 (343)

On the extraction of resistivity and area of nanoscale interconnect lines by temperature-dependent resistance measurements

, 2018
Several issues concerning the applicability of the temperature coefficient of the resistivity (TCR) method to scaled interconnect lines are discussed. The central approximation of the TCR method, the substitution of the interconnect wire TCR by the bulk ...
Adelmann, Christoph
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Mixed-Methods Analysis of Barriers and Enablers to Implementation of Lung Protective Ventilation Adherence [PDF]

, 2020
Daniel Hynes, Emily Johnson, Nandita R. Nadig, Daniel Brinton, Annie N. Simpson, Katherine R. Sterba, Andrew Goodwin, Dee W. Ford   +7 more
openalex   +1 more source

Barriers for Adult Patients to Access Palliative Care in Hospitals: A Mixed Methods Systematic Review [PDF]

, 2023
Stefan Pitzer, Patrick Kutschar, Piret Paal, Patrick Mülleder, Stefan Lorenzl, Paulina Wosko, Jürgen Osterbrink, Johannes Bükki   +7 more
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Synchronous reluctance machine design considering slotting effect and rotor topology optimization

Engineering Science and Technology, an International Journal
This research explores design criteria for a synchronous reluctance machine (SynRM) with a four-layer rotor flux barrier structure with different design shapes. The main focus is to investigate slot harmonics and the angle influence of rotor flux barrier
Sayyed Haleem Shah, Omer Mohammed Elbabo Mohammed, Sadiq Ur Rahman, Hui Cai   +3 more
doaj   +1 more source

Combined acoustical and economical noise barrier optimization using genetic algorithms

Građevinar, 2019
This paper studies noise barrier optimization using the Boundary Element Method (BEM) as a numerical technique and Genetic Algorithms (GA). Noise barriers are optimised according to acoustical, technological and economical properties so as to obtain an ...
Antonio Petošić, Mia Suhanek, Ivan Đurek, Sanja Grubeša   +3 more
doaj   +1 more source

Barrier modification in sub-barrier fusion reactions using Wong formula with Skyrme forces in semiclassical formalism

, 2010
We obtain the nuclear proximity potential by using semiclassical extended Thomas Fermi (ETF) approach in Skyrme energy density formalism (SEDF), and use it in the extended $\ell$-summed Wong formula under frozen density approximation. This method has the
Arun S K, Bansal M, Gupta R K, Gupta R K, Gupta R K, Kumar R, Li G-Q, Raj K Gupta, Raj Kumar, Royer G, See   +10 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Maximising mosquito collections from barrier screens: the impacts of physical design and operation parameters

Parasites & Vectors, 2019
Background Traditional methods for collecting outdoor resting mosquitoes are generally inefficient with relatively low numbers caught per unit effort. The barrier screen, designed to intercept mosquitoes as they fly between areas where blood meals are ...
Edgar J. M. Pollard, Tanya L. Russell, Thomas R. Burkot   +2 more
doaj   +1 more source