Results 71 to 80 of about 1,327,323 (292)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Disruptive Innovation: Enabling Practitioners to Tackle the "Innovators Dilemma" With Graphical Techniques - A Focus on Resource Allocation [PDF]
, 2004 This paper presents the findings of part of a 30 month investigation, conducted to better understand the persistent failure of management practitioners to fund potentially disruptive innovations. A Mode 2 case study strategy was employed.
Herzberg, Torsten +2 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Possible strategies to cross the blood–brain barrier [PDF]
Italian Journal of Pediatrics, 2018 The mucopolysaccharidoses (MPS) are a heterogeneous group of in-born metabolic conditions caused by genetic defects that result in the absence or severe deficiency of one of the lysosomal hydrolases responsible for the degradation of glycosaminoglycans (GAGs).
Bellettato, Cinzia M., Scarpa, Maurizio
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Ain Shams Engineering JournalThis paper proposes a barrier function-based adaptive control strategy with a nonlinear sliding surface for a class of uncertain dynamic systems with input saturation.
Rahim Rahimpour +6 more
doaj +1 more source
From Safety Net to Self Sufficiency: A CJC Proposal for a State Mixed Strategy Approach to Prepare TANF and Food Stamp Employment and Training Participants for Illinois' Skilled Workforce [PDF]
, 2003 Report details CJC's recommendation that Illinois Department of Human Services (IDHS) adopt a mixed strategy approach for Illinois' TANF and Food Stamp E&T programs.
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Great Barrier Reef Biodiversity Conservation Strategy 2012 [PDF]
, 2012 The draft Great Barrier Reef Biodiversity Conservation Strategy 2012 provides a framework for improving biodiversity conservation in the Great Barrier Reef Region.
core
Cross-Modal Data Programming Enables Rapid Medical Machine Learning
, 2019 Labeling training datasets has become a key barrier to building medical machine learning models. One strategy is to generate training labels programmatically, for example by applying natural language processing pipelines to text reports associated with ...
Dunnmon, Jared +10 more
core +1 more source