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Immunity at the Barriers [PDF]
European Journal of Immunology, 2013 Maintenance of barrier defense is an essential component of mammalian host health and survival. Most antigens encountered by the immune system enter the body through the skin or mucosal surfaces of the respiratory, gastrointestinal, and urogenital tract. The vast majority of infectious microorganisms use these tissues as portals of entry. An additional
David Artis, Yasmine Belkaid
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FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Journal of Interactive Media in Education, 2021 The Covid-19 pandemic has raised significant challenges for universities. Digital inclusion “of all learners regardless of their circumstances, learning prerequisites and needs” is a major challenge (Walgenbach, Compes & Lambrich 2019: 9, authors ...
Lisa Ulzheimer +6 more
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Most vital segment barriers [PDF]
, 2019 We study continuous analogues of "vitality" for discrete network flows/paths, and consider problems related to placing segment barriers that have highest impact on a flow/path in a polygonal domain.
B Chazelle +22 more
core +2 more sources
PLoS ONE, 2017 Background Influenza vaccine hesitancy is a significant threat to global efforts to reduce the burden of seasonal and pandemic influenza. Potential barriers of influenza vaccination need to be identified to inform interventions to raise awareness ...
Philipp Schmid +4 more
semanticscholar +1 more source
The Canadian Journal of Psychiatry, 1984 In elevating cost containment to a first principle, the current political debate about health policy in the U.S. and Canada has lost sight of what should be its primary concern: the health status of the population. The two need not be incompatible. Many current medical procedures are of uncertain value for health and entail sizable costs.
openaire +3 more sources
FEBS Letters, EarlyView.To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche +2 more
wiley +1 more source
Journal of Pediatrics Review, 2021 Background: Adolescents need services that improve their physiological, cognitive, emotional, and social alteration into adulthood. Since the adolescent health needs have been identified, the focus of service delivery has mainly been on access to sexual ...
Farzane Alidost +3 more
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Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Heliyon, 2019 In view of increasing numbers of dermatological disorders, transdermal drug delivery along with in vitro research is becoming increasingly popular. Herefore, qualified in vitro skin models are required.
I. Bauhammer, M. Sacha, E. Haltner
doaj