Results 61 to 70 of about 3,618,266 (313)

Barriers in Quantum Gravity

, 1993
I discuss recent progress in our understanding of two barriers in quantum gravity: $c > 1$ in the case of 2d quantum gravity and $D > 2$ in the case of Euclidean Einstein-Hilbert gravity formulated in space-time dimensions $D >2$.Comment: standard latex,
Ambjorn, Jan
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Adipose‐derived mesenchymal stem cell‐incorporated PLLA porous microspheres for cartilage regeneration

Animal Models and Experimental Medicine
Background In facial plastic surgery, patients with nasal deformity are often treated by rib cartilage transplantation. In recent years, cartilage tissue engineering has developed as an alternative to complex surgery for patients with minor nasal defects
Chang Gao, Wenlong Yuan, Dongcheng Wang, Xin Zhang, Tong Zhang, Zhimin Zhou   +5 more
doaj   +1 more source

Dark costs, missing data: shedding some light on services trade [PDF]

, 2015
A structural gravity model is used to estimate barriers to services trade across many sectors, countries and time. Since the disaggregated output data needed to flexibly infer border barriers are often missing for services, we derive a novel ...
Anderson, James E, Borchert, Ingo, Mattoo, Aaditya, Yotov, Yoto   +3 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Level Crossing Along Sphaleron Barriers

, 1994
In the electroweak sector of the standard model topologically inequivalent vacua are separated by finite energy barriers, whose height is given by the sphale\-ron.
A. Ringwald, A. Ringwald, B. Kleihaus, C. R. Nohl, D. Diakonov, E. W. Kolb, F. R. Klinkhamer, F. R. Klinkhamer, G. 't Hooft, G. Nolte, J. Boguta, J. Kunz, J. Kunz, J. Kunz, Jutta Kunz, L. Carson, L. G. Yaffe, N. S. Manton, P. Arnold, P. Arnold, R. F. Dashen, T. Akiba, V. A. Kuzmin, Y. Brihaye, Y. Brihaye, Yves Brihaye   +25 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Peer-led problem-based learning in interprofessional education of health professions students [PDF]

Medical Education Online, 2015
Background: The role of peer teachers in interprofessional education has not been extensively studied. This study is designed to determine if peer-teacher-led problem-based seminars can influence medical and pharmacy students’ perceptions of ...
Michael D. Lehrer, Samuel Murray, Ruth Benzar, Ryan Stormont, Megan Lightfoot, Michael Hafertepe, Gabrielle Welch, Nicholas Peters, Anna Maio   +8 more
doaj   +1 more source

Tunneling without barriers with gravity

, 2012
We consider the vacuum decay of the flat Minkowski space to an anti-de Sitter space. We find a one-parameter family of potentials that allow exact, analytical instanton solutions describing tunneling without barriers in the presence of gravity.
Kanno, Sugumi, Sasaki, Misao, Soda, Jiro
core   +1 more source