Results 81 to 90 of about 980,683 (314)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

A benzothiazole-based new fluorogenic chemosensor for the detection of CN⁻ and its real-time application in environmental water samples and living cells

, 2022
Dhanapal Jothi, Sathishkumar Munusamy, Selin Manoj Kumar, Saravanan Enbanathan, Sathiyanarayanan Kulathu Iyer   +4 more
openalex   +2 more sources

Design and optimization of non-toxic and highly efficient tin-based organic perovskite solar cells by device simulation [PDF]

, 2023
Manisha Ahamad, A. K. M. Akther Hossain
openalex   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Vulvar basal cell carcinoma

Indian Journal of Pathology and Microbiology, 2012
Although the basal cell carcinoma (BCC) is the most common malignancy of skin, it is rarely seen in vulva and constitutes 2% to 4% of all vulvar cancers. The cause is unknown but, chronic vulvar irritation is the most important underlying factor.
Mustafa Kara, E Colgecen, Erdogan Nilsen Yildirim   +2 more
doaj   +1 more source

Machine Learning-Enabled Renal Cell Carcinoma Status Prediction Using Multiplatform Urine-Based Metabolomics

, 2021
Olatomiwa O. Bifarin, David A. Gaul, Samyukta Sah, Rebecca S. Arnold, Kenneth Ogan, Viraj A. Master, David L. Roberts, Sharon Bergquist, John A. Petros, Facundo M. Fernández, Arthur S. Edison   +10 more
openalex   +2 more sources

Targeting Cancer Cell Tight Junctions Enhances PLGA-Based Photothermal Sensitizers’ Performance In Vitro and In Vivo [PDF]

, 2021
Victoria O. Shipunova, Vera L. Kovalenko, Polina A. Kotelnikova, Anna S. Sogomonyan, О. Н. Шилова, Elena N. Komedchikova, Andrei V. Zvyagin, Maxim P. Nikitin, Sergey M. Deyev   +8 more
openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Histomorphological evaluation of skin lesions at the Kadapa Government Medical College teaching institute: A two-year study [PDF]

Journal of Clinical and Basic Research
Background: The prevalence of skin diseases varies geographically due to factors, such as etiology, environment, genetics, and lifestyle. The current study aimed to determine the incidence and distribution of skin disorders and to provide a description ...
Velpula Nagesh Kumar, Shaik Raja Husne Kalam, Polisetty Satya Narayana Rao, Gollapalli Sobha Rani   +3 more
doaj  

Junction formation by Zn(O,S) sputtering yields CIGSe-based cells with efficiencies exceeding 18% [PDF]

, 2013
R. Klenk, Alexander Steigert, T. Rissom, D. Greiner, Christian A. Kaufmann, Thomas Unold, Martha Ch. Lux‐Steiner   +6 more
openalex   +1 more source