Results 101 to 110 of about 4,068 (202)

Activating Smoothened mutations in sporadic basal-cell carcinoma

, 1998
Basal-cell carcinomas (BCCs) are the commonest human cancer. Insight into their genesis came from identification of mutations in the PATCHED gene (PTCH) in patients with the basal-cell nevus syndrome, a hereditary disease characterized by multiple BCCs ...
Mary Hynes, Xie, J, Jingwu Xie, Goddard, A, Chaohui Zhang, Gu, Q, Lam, CW, Maximilien Murone, Luoh, SM, Audrey Goddard, Bonifas, JM, Ching-Wan Lam, Shiuh-Ming Luoh, Anne Ryan, Arnon Rosenthal, Frederic J. de Sauvage, Ervin H Epstein, Rosenthal, A, Hynes, M, Jeannette M. Bonifas, Qimin Gu, Murone, M, Zhang, C, De Sauvage, FJ, Ryan, A, Epstein Jr, EH   +25 more
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The hedgehog pathway in basal cell carcinoma

, 2020
The hedgehog pathway, consisting partly of patched-1 (PTCH1) and smoothened (SMO), is essential in the development of basal cell carcinomas (BCCs). In 2012 vismodegib, a hedgehog pathway inhibitor, registered for the treatment of advanced BCCs (aBCCs ...
Verkouteren, B. J.A., Mosterd, Klara
core   +1 more source

A case of basal cell nevus syndrome

Japanese Journal of Oral & Maxillofacial Surgery, 1976
OHTANI, Takatoshi, FUKUDA, Hiroshi, FUNAKOSHI, Tatsumi, MOGI, Shigeo, KOJIMA, Masahiro, MASUDA, Masaki, OHTA, Shun   +6 more
openaire   +3 more sources

Gorlin'S Syndrome: An Interesting Case Study and Literature Review

, 2004
Gorlin's Syndrome, Or Basal Cell Nevus Syndrome, Is a Relatively Rare Disease. It Consists of a Classic Pentad of Features Comprised of Multiple Basal Cell Carcinomas, Jaw Cysts, Calcification of the Falx Cerebri, Pitting of the Palmar and Plantar ...
Robyn J Watts, Justin Paletz
core   +1 more source

Basal Cell Carcinoma with Flexural Predilection in Basal Cell Nevus Syndrome.

Indian Dermatol Online J, 2021
Ashraf R, Kaushik A, Gupta K, Vinay K.
europepmc   +1 more source

Basal Cell Nevus Syndrome [PDF]

Archives of Dermatology, 2010
Leonard H, Goldberg, Bahar F, Firoz, Glen J, Weiss, Lisa, Blaydorn, Gayle, Jameson, Daniel D, Von Hoff   +5 more
openaire   +2 more sources

Basal cell nevus syndrome. Presentation of six cases and literature review

, 2005
El síndrome névico baso-celular, también conocido como síndrome de Gorlin-Goltz, es un trastorno de herencia autosómica dominante que se caracteriza por la presencia de queratoquistes múltiples maxilares y carcinomas basocelulares faciales, junto con ...
Ruíz Laza, L., Belmonte Caro, Rodolfo, García-Perla García, Alberto, Gutiérrez Pérez, José Luis, Díaz-Fernández, José María, Infante Cossío, Pedro Antonio   +5 more
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THREE CASES OF BASAL CELL NEVUS SYNDROME IN ONE FAMILY

, 1992
In this paper, 3 cases with manifestations of basal cell nevus syndrome in one Japanese Family are described. In the cases of an 8-year-old female, a 12-year-old female and a 40-year old male, idential symptoms such as multiple odontogenic jaw (kerato ...
藪内, 久, 川上, 哲司, 匠原, 悦雄, 竹内, 尚則, 望月, 光治, 大槻, 栄人, 杉村, 正仁   +6 more
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Odontogenic keratocysts are an important clue for diagnosing basal cell nevus syndrome

Basal cell nevus syndrome (BCNS) is an autosomal dominant skin disorder characterized by multiple basal cell nevi. Patients with BCNS tend to develop basal cell carcinoma (BCC) and frequently show skeletal abnormalities.
Kaibuchi-Ando, Kaori, Takeichi, Takuya, Yamada, Motohito, Ogi, Tomoo, Yamashita, Yuta, Muro, Yoshinao, Akiyama, Masashi, Takeuchi, So, Ito, Yasutoshi   +8 more
core  

Efficacy of combined topical imiquimod, 5-fluorouracil, and tretinoin in the treatment of a basaloid atypical proliferation on the plantar surface in a patient who is nonsyndromic for basal cell nevus syndrome. [PDF]

JAAD Case Rep
Nahm WJ, Badiavas EV, Kirsner RS, Shen CL, Elgart GW.   +4 more
europepmc   +1 more source