Results 71 to 80 of about 157,060 (309)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease

, 2001
The extent of synchronization within and between the nuclei of the basal ganglia is unknown in Parkinson's disease. The question is an important one because synchronization will increase postsynaptic efficacy at subsequent projection targets.
Peter Brown, Vincenzo Di Lazzaro, Oliviero, A, Insola, A, Brown, Peter, Antonio Oliviero, Di Lazzaro, V, Mazzone, P, Brown, P, Pietro Tonali, Tonali, P, Paolo Mazzone, Angelo Insola   +12 more
core   +1 more source

Characterisation and segmentation of basal ganglia mineralization in normal ageing with multimodal structural MRI [PDF]

, 2016
Iron is the most abundant trace metal in the brain and is essential for many biological processes, such as neurotransmitter synthesis and myelin formation.
Glatz, Andreas
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Microsurgical and Functional Linguistic Anatomy of Cerebral Basal Ganglia

İstanbul Medical Journal, 2020
Introduction:The central core of the cerebral hemispheres is located on the medial side of the insular cortex. It is made up of basal ganglia and white matter tracts.
Mustafa Güdük, Musa Çırak, Baran Bozkurt, Kaan Yağmurlu   +3 more
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

The molecular, cellular, and systems-level structure of the basal ganglia

, 2018
This chapter provides a brief overview of the systems, cellular, and molecular structure of the various nuclei of basal ganglia (BG) such as striatum, STN, GPe, GPi, and the SNr including the various neurotransmitters impacting its function.
V. Srinivasa Chakravarthy, Mandali, Alekhya, Chakravarthy, Srinivasa, Ahmed A. Moustafa, Moustafa, Ahmed A. (R17078), Alekhya Mandali   +5 more
core   +1 more source

The Cortico-Basal Ganglia-Cerebellar Network: Past, Present and Future Perspectives

Frontiers in Systems Neuroscience, 2019
Much of our present understanding of the function and operation of the basal ganglia rests on models of anatomical connectivity derived from tract-tracing approaches in rodents and primates.
Demetrio Milardi, Demetrio Milardi, Angelo Quartarone, Alessia Bramanti, Giuseppe Anastasi, Salvatore Bertino, Gianpaolo Antonio Basile, Piero Buonasera, Giorgia Pilone, Giuseppe Celeste, Giuseppina Rizzo, Daniele Bruschetta, Alberto Cacciola   +12 more
doaj   +1 more source

Migraine Attacks the Basal Ganglia

Molecular Pain, 2011
Background: With time, episodes of migraine headache afflict patients with increased frequency, longer duration and more intense pain. While episodic migraine may be defined as 1-14 attacks per month, there are no clear-cut phases defined, and those patients with low frequency may progress to high frequency episodic migraine and the latter may progress
Bigal Marcelo, Brawn Jennifer, Pendse Gautam, Nutile Lauren, Becerra Lino, Maleki Nasim, Burstein Rami, Borsook David   +7 more
openaire   +3 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source