Results 211 to 220 of about 70,366 (259)
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MRI in basal ganglia diseases

1991
76 patients suffering from different basal ganglia diseases (28 cases with M. Parkinson, secondary parkinsonism and Parkinson diseases; 5 cases with Chorea Huntington; 5 cases with Fahr disease and 38 cases with M. Wilson) MRI featured 2 characteristical patterns: 1. abnormal deposition of minerals, 2. focal atrophies of involved organs.
D, Wimberger   +4 more
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Dopamine and Basal Ganglia Diseases

Archives of Neurology, 1961
In July 1957, at the First International Congress of Neurological Sciences in Brussels, J. N. Cumings summarized the state of our knowledge on the biochemistry of basal ganglia diseases in one sentence: "The biochemical pathologist has so far been of practical assistance to the clinical neurologist and to the patient in only one of the group of ...
openaire   +2 more sources

Pathophysiology of the basal ganglia in Parkinson's disease

Trends in Neurosciences, 2000
Insight into the organization of the basal ganglia in the normal, parkinsonian and L-dopa-induced dyskinesia states is critical for the development of newer and more effective therapies for Parkinson's disease. We believe that the basal ganglia can no longer be thought of as a unidirectional linear system that transfers information based solely on a ...
J A, Obeso   +6 more
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Genetic diagnosis of basal ganglia disease in childhood

Developmental Medicine & Child Neurology, 2022
AIMTo correlate clinical, radiological, and biochemical features with genetic findings in children with bilateral basal ganglia lesions of unknown aetiology, and propose a diagnostic algorithm for early recognition.METHODChildren with basal ganglia disease were recruited in a 2‐year prospective multicentre study for clinical, biomarker, and genetic ...
Heidy Baide‐Mairena   +9 more
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Basal ganglia activation in Parkinson's disease

Parkinsonism & Related Disorders, 2006
The objective of this study was to compare basal ganglia activation in patients with Parkinson's disease to that of healthy controls, using functional MRI (fMRI). Six mildly-affected patients, off antiparkinsonian medications for at least 12h, and seven age-matched controls performed a unilateral motor switching task during fMRI data acquisition. Clear
A, Holden   +3 more
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Excretion of Dopamine in Diseases of Basal Ganglia

Science, 1961
The urinary excretion of catecholamines has been measured in 32 patients with disorders of the basal ganglia. Sixteen patients with Parkinsonism (idiopathic, postencephalitic, and arteriosclerotic types) had a significantly lower amount of dopamine in the urine during a 24-hour period than a group of 24 normal control subjects.
A, BARBEAU, G F, MURPHY, T L, SOURKES
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Neurophysiology of basal ganglia diseases

2007
Publisher Summary This chapter discusses the neurophysiology of basal ganglia diseases. The anatomical structures of the basal ganglia are connected to each other by a network of interconnections and the functional organization is based on the connections with thalamus and cortical territories.
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Diseases of the Basal Ganglia

1984
There are various conditions in which involuntary movements develop and in which pathological changes are present in the basal ganglia. Some of these conditions, and especially paralysis agitans, have been the subject of intense study during the past two decades.
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Mitochondrial defects in basal ganglia diseases

Current Opinion in Neurology, 1995
Mitochondrial DNA mutations are important causes of movement disorders and are often associated with basal ganglia degeneration. Leigh's disease and a form of generalized dystonia are caused by mitochondrial DNA mutations. Recent biochemical and genetic evidence suggests that some cases of Parkinson's disease may be caused by oxidative phosphorylation ...
openaire   +2 more sources

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