Results 181 to 190 of about 559,417 (315)
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Bell's palsy and prednisolone. [PDF]
Joel Desmond, P. Wallman
openalex +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Clonal integration and Bacillus subtilis modulate Glechoma longituba performance and soil microbial communities. [PDF]
Zhao BN, Wang XG, Zhang R, He XG, Si C.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Neutrophil Function in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. [PDF]
Lauxen JS+11 more
europepmc +1 more source
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Topical analgesia in corneal abrasions. [PDF]
Simon Carley
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Hippo Pathway Regulates Cell Proliferation in Skin Epidermis Exposed to Mechanical Forces. [PDF]
Ledwon JK+7 more
europepmc +1 more source