Results 261 to 270 of about 559,417 (315)

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Artificial Intelligence Performance in Cardiac Magnetic Resonance Strain Analysis for Aortic Stenosis: Validation with Echocardiography and Healthy Controls. [PDF]

Medicina (Kaunas)
Abramikas Ž, Jasiukevičiūtė I, Balčiūnaitė G, Glaveckaitė S, Palionis D, Valevičienė N.   +5 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Single-cell profiling demonstrates the combined effect of wheeze phenotype and infant viral infection on airway epithelial development. [PDF]

Sci Adv
Berdnikovs S, Newcomb DC, Haruna NF, McKernan KE, Kuehnle SN, Gebretsadik T, McKennan C, Ma S, Cephus JY, Rosas-Salazar C, Anderson LJ, Gern JE, Hartert T.   +12 more
europepmc   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Corrigendum: Case report: A novel PTCH1 frameshift mutation leading to nevoid basal cell carcinoma syndrome. [PDF]

Front Med (Lausanne)
Lang X, Wang T, Guo S, Dang Y, Zhang Y, Liu H, He H, Li L, Yuan H, He T, Wang Q, Qin S, Cheng R, Yan X, Cui H.   +14 more
europepmc   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Insect fat influences broiler performance, meat quality, and the cecal microbiota similarly to plant oils rather than animal fats. [PDF]

Sci Rep
Aslam MR, Kierończyk B, Rawski M, Szymkowiak P, Stuper-Szablewska K, Kołodziejski P, Mikuła R, Dankowiakowska A, Józefiak D.   +8 more
europepmc   +1 more source

Deep brain stimulation for dystonia treatment in cerebral palsy: efficacy exploration. [PDF]

Exp Biol Med (Maywood)
Zheng H, Zhang D, Xiang W, Gan Y, Peng Z, Wu Y, Fu P.   +6 more
europepmc   +1 more source

HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity. [PDF]

Nat Commun
Dobersch S, Yamamoto N, Schutter A, Cavender SM, Robertson TM, Kartha N, Samraj AN, Doron B, Poole LA, Wladyka CL, Zhang A, Jang GH, Mahalingam AH, Barreto G, Raghavan S, Narla G, Notta F, Eisenman RN, Hsieh AC, Kugel S.   +19 more
europepmc   +1 more source