Results 271 to 280 of about 938,616 (362)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Feasibility and Safety of Stereotactic Hematoma Aspiration via Supraorbital Keyhole Route in Patients With Basal Ganglia Spontaneous Intracerebral Hemorrhage: A Single Center Retrospective Analysis. [PDF]

J Korean Med Sci
Kim JH, Lee S, Park DH, Kang SH, Park KJ.   +4 more
europepmc   +1 more source

Reviews on evidence-based cancer medicine

, 1998
C. J. Williams, Jonathan J Deeks
openalex   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Prenatal exposure to extreme ambient heat may amplify the adverse impact of Superstorm Sandy on basal ganglia volume among school-aged children. [PDF]

PLoS One
DeIngeniis D, Blum M, Lee RM, Shereen AD, Nomura Y.   +4 more
europepmc   +1 more source

A trial of image data base construction for medicine by a personal computer

, 1998
Youji Kumatani, Osamu Hiruma, Hideaki Okamoto, Keiji Kasai, Hiroshi Maeda, Yasuo Hiura, C Kuroda, Satoshi Sumitsuji   +7 more
openalex   +2 more sources

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Proliferation and regeneration of the healthy human urothelium: A multi-scale simulation approach with 16 hypotheses of cell differentiation. [PDF]

PLoS One
Siegel F, Torelli A, Mattis M, Debatin J, Erben P, Gumbel M.   +5 more
europepmc   +1 more source