Results 291 to 300 of about 30,761,260 (406)

Ejection Fraction-Related Differences in Left Ventricular and Atrial Strain Indices Among Pediatric Fontan Circulation with Systemic Left Ventricle Morphology. [PDF]

Diagnostics (Basel)
Șuteu CC, Fagarasan A, Suteu N, Cerghit-Paler A, Gozar L, Mărginean CO, Săsăran MO, Iancu M.   +7 more
europepmc   +1 more source

OP-5 A novel curriculum: incorporating transformative learning theory-based narrative medicine modules into palliative care physician training [PDF]

P.K. Kuruvilla
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Multiple Primary Lung Cancer With Driver Gene Mutations: Is Targeted Therapy Always the Optimal Choice?-A Case Report. [PDF]

Thorac Cancer
Ren ZR, Wu L, Lu C, Wang F, Peng YL, Cai DX, Tang LB, Li JT, Guo Z, Chen ZH, Deng Y, Sun L, Wei XW, Huang QL, Xu CR, Zhou Q.   +15 more
europepmc   +1 more source

Enhanced Adenosine Triphosphate Release From the Urothelium of Patients With Painful Bladder Syndrome:A Possible Pathophysiological Explanation [PDF]

, 2007
Chapple, Christopher R., Chess-Williams, Russell, Kumar, Vivek, Surprenant, Ann Marie   +3 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A Presentation of Fungating Nevoid Basal Cell Carcinoma Syndrome. [PDF]

Cureus
Ogunremi OO, Hannahs B, Hockhausen K.
europepmc   +1 more source

Integrative treatment of granulomatosis with polyangiitis based on the traditional Chinese medicine principle of soothing the liver, promoting blood circulation, resolving phlegm, and dispersing nodules [PDF]

Tingting Zhu, Zhenjie Chen, Xiaowei Chen, Hong Cui, Yingying Liu, Wei Gao, Xionggao Han, Y Bian, Liyan Wang, M. Shao, Zhicai Shi   +10 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source