Results 291 to 300 of about 938,616 (362)

Single-cell analysis of gene regulatory networks in the mammary glands of P4HA1-knockout mice. [PDF]

PLoS Genet
Gupta A, Huang L, Liu J, Chen K, Xu R, Wu W.   +5 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Prevalence of genetic alterations in basal cell carcinoma patients resistant to Hedgehog pathway inhibitors: a systematic review. [PDF]

Ann Med
Untaaveesup S, Srichana P, Techataweewan G, Pongphaew C, Dendumrongsup W, Ponvilawan B, Nampipat N, Limwongse C.   +7 more
europepmc   +1 more source

Altered dendritic morphology of MEC II pyramidal and stellate cells in Rett syndrome mice. [PDF]

Front Neuroanat
Krishnan M, Mydeen AB, Nakhal MM, Ibrahim MF, Jayaraj RL, Ljubisavljevic MR, Hamad MIK, Ismail FY.   +7 more
europepmc   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Differential BACH1 Expression in Basal-like Breast Tumors of Black Women Identified via Immunohistochemistry. [PDF]

Curr Oncol
Dowling NM, Khramtsova G, Olopade O, Samankan S, Lee BS, Lee J.   +5 more
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Educational Case: Squamous cell carcinoma. [PDF]

Acad Pathol
Scholl AR, Flanagan MB, Thompson AD.
europepmc   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

In-depth analysis of risk factors for postoperative pulmonary infection in patients with basal ganglia haemorrhage and construction of prediction model: based on domestic and international cutting-edge clinical research and big data analysis. [PDF]

Front Med (Lausanne)
Chen M, Da L, Huang C, Liu J, Tang J, Zha Z.   +5 more
europepmc   +1 more source