Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source
Preventing the phosphorylation of RyR2 at canonical sites reduces Ca<sup>2+</sup> leak and promotes arrhythmia by reactivating the I<sub>Na</sub> current. [PDF]
Zheng J+6 more
europepmc +1 more source
PoDCall: a robust tool for automated droplet classification in DNA‐methylation droplet digital PCR
Molecular Oncology, EarlyView.
Hans Petter Brodal+3 more
wiley +1 more source
Electro-Acupuncture for Diminished Ovarian Reserve: Protocol for a Randomized, Placebo-Controlled Trial. [PDF]
Tang H+9 more
europepmc +1 more source
Stem cell CNTF promotes olfactory epithelial neuroregeneration and functional recovery following injury. [PDF]
Cox D+6 more
europepmc +1 more source
Characteristics of oocyte fertilization and early embryo development in infertile women with different ovarian reserves in the Changde region, China. [PDF]
Li D+6 more
europepmc +1 more source
Common Basal Concept in Primary Care Medicine and Psychosomatic Medicine
openaire
Basal-shift transformation leads to EGFR therapy-resistance in human lung adenocarcinoma. [PDF]
Shinozaki T+33 more
europepmc +1 more source
SGLT2 inhibitor therapy in overweight and obese patients with cystic fibrosis-related diabetes: Case series. [PDF]
Ahmed A+3 more
europepmc +1 more source