Results 31 to 40 of about 559,417 (315)

The impact of graft size on the development of dyskinesia following intrastriatal grafting of embryonic dopamine neurons in the rat

Neurobiology of Disease, 2006
Intrastriatal transplants of embryonic ventral mesencephalon can cause dyskinesia in patients with Parkinson's disease (PD). We assessed the impact of transplant size on the development of graft-induced dyskinesia.
E.L. Lane, C. Winkler, P. Brundin, M.A. Cenci   +3 more
doaj  

Fermented Chinese Herbal Medicine Promoted Growth Performance, Intestinal Health, and Regulated Bacterial Microbiota of Weaned Piglets

Animals, 2023
To investigate the effects of fermented Chinese herbal medicine on growth performance, diarrhea rate, nutrient digestibility, and intestinal health of weaned piglets, and to provide the theoretical basis for applying fermented Chinese herbal medicines to
Guang Chen, Zhiqing Li, Shuangli Liu, Tuo Tang, Qinghua Chen, Zhaoming Yan, Jie Peng, Zhikang Yang, Guanfeng Zhang, Yating Liu, Mengli Zheng   +10 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

The Effect of a Hyperdynamic Circulation on Tissue Doppler Values: A Simulation in Young Adults during Exercise

Anesthesiology Research and Practice, 2011
Left ventricular tissue Doppler imaging (TDI) velocities are used to monitor systolic and diastolic function, but it is not known how these may change in a hyperdynamic circulation, as often occurs in anesthesia and critical care medicine.
Colin F. Royse, Ni Ruizhi, Andrew L. Huynh, Alistair G. Royse   +3 more
doaj   +1 more source

Basal cell carcinoma. Diagnostic and therapeutic recommendations of Polish Dermatological Society

Przegląd Dermatologiczny, 2019
Incidence of skin cancers is constantly increasing, what constitutes a significant epidemiologic problem of modern medicine. Basal cell carcinoma is the most common neoplasm affecting Caucasians.
Aleksandra Lesiak, Joanna Czuwara, Grażyna Kamińska-Winciorek, Dorota Kiprian, Joanna Maj, Witold Owczarek, Waldemar Placek, Lidia Rudnicka, Piotr Rutkowski, Michał Sobjanek, Małgorzata Sokołowska-Wojdyło, Jacek Szepietowski, Barbara Zegarska, Wojciech Zegarski   +13 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Challenges and unmet needs in basal insulin therapy: lessons from the Asian experience

Diabetes, Metabolic Syndrome and Obesity, 2017
Wing Bun Chan,1 Jung Fu Chen,2 Su-Yen Goh,3 Thi Thanh Huyen Vu,4 Iris Thiele Isip-Tan,5 Sony Wibisono Mudjanarko,6 Shailendra Bajpai,7 Maria Aileen Mabunay,7 Pongamorn Bunnag8 1Qualigenics Diabetes Centre, Hong Kong SAR, People’s Republic of China;
Chan WB, Chen JF, Goh SY, Vu TTH, Isip-Tan IT, Mudjanarko SW, Bajpai S, Mabunay MA, Bunnag P   +8 more
doaj  

Transplantation of Basal Cell Epitheliomas**From the Departments of Dermatology and Pathology, Baylor University College of Medicine, Houston, Texas.

Journal of Investigative Dermatology, 1960
The nature and behavior of basal cell epitheliomas have been the subject of much discussion. There are those who do not consider these lesions to be true malignant neoplasms. However, a few instances of metastasis have been described (1). Pickren and Katz (2) suggested that metastasis may occur by direct implantation to mucous membrane. The possibility
Thomas W. Lyles, John M. Knox, Robert G. Freeman   +2 more
openaire   +3 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source