Quantification of left ventricular longitudinal strain, strain rate, velocity and displacement in healthy horses by 2-dimensional speckle tracking [PDF]
Background: The quantification of equine left ventricular (LV) function is generally limited to short-axis M-mode measurements. However, LV deformation is 3-dimensional (3D) and consists of longitudinal shortening, circumferential shortening, and radial ...
De Clercq, Dominique+4 more
core +1 more source
The Serine/Threonine Protein Kinase (Akt)/ Protein Kinase B (PkB) Signaling Pathway in Breast Cancer [PDF]
According to statistical data published in 2019, breast cancer is among the leading causes of death in women worldwide. The serine/threonine kinase (AKT) or protein kinase B (PkB) signaling pathway is activated by phosphorylation processes, which further
Bratu, Ovidiu Gabriel+8 more
core +3 more sources
The effects of biota (Biota orientalis ENDL.) on learning impairment produced by bilateral lesion of basal forebrain in mice were studied using step-through and step-down type passive avoidance tasks. Basal forebrain-lesion was generated by applying radiofrequency current. Behavioral experiment, started 15d after the survey, revealed prominent delay in
Hiroshi Saito+2 more
openaire +4 more sources
NRF2 regulates HER1 signaling pathway to modulate the sensitivity of ovarian cancer cells to lapatinib and erlotinib [PDF]
NF-E2-related factor 2 (NRF2) regulates the transcription of a battery of metabolic and cytoprotective genes. NRF2 and epidermal growth factor receptors (EGFRs/HERs) are regulators of cellular proliferation and determinants of cancer initiation and ...
Bown, James L.+5 more
core +11 more sources
Impact of aging : sporadic, and genetic risk factors on vulnerability to apoptosis in Alzheimer's disease [PDF]
The identification of specific genetic (presenilin-1 [PS1] and amyloid precursor protein [APP] mutations) and environmental factors responsible for Alzheimer's disease (AD) has revealed evidence for a shared pathway of neuronal death.
Czech, Christian+11 more
core +1 more source
The major advances in the area of movement disorders in Brazil in recent years were driven by the work of Luiz Augusto Franco de Andrade and Egberto Reis Barbosa.
Hélio Afonso Ghizoni Teive+4 more
doaj +1 more source
MRI and Neuropsychological Correlates of Carbon Monoxide Exposure: A Case Report [PDF]
A 45-year-old woman experienced long-term, chronic exposure to carbon monoxide in the restaurant kitchen where she was employed as a cook. After returning to the restaurant after 5 days off work, she noticed that her symptoms returned immediately; she ...
Bunnell DE+9 more
core +3 more sources
Joint and individual analysis of breast cancer histologic images and genomic covariates [PDF]
A key challenge in modern data analysis is understanding connections between complex and differing modalities of data. For example, two of the main approaches to the study of breast cancer are histopathology (analyzing visual characteristics of tumors ...
Calhoun, Benjamin C.+10 more
core +3 more sources
Objective: The aim of this study is to report the improvement of a basal ganglia infarction patient with left hemiplegia and gait disturbance after treatment with Korean medicine.Methods: The patient was treated using acupuncture, moxibustion, and herbal medicine.
Ji-hae Yang+6 more
openaire +1 more source
The Effect of High Dose Total Body Irradiation on ACTH, Corticosterone, and Catecholamines in the Rat [PDF]
Total body irradiation (TBI) or partial body irradiation is a distinct risk of accidental, wartime, or terrorist events. Total body irradiation is also used as conditioning therapy before hematopoietic stem cell transplantation.
Bruder, Eric D.+4 more
core +2 more sources