Results 71 to 80 of about 559,417 (315)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Selegiline remarkably improved stage 5 treatment-resistant major depressive disorder: a case report

open access: yesNeuropsychiatric Disease and Treatment, 2013
Yuji Kitaichi,1 Takeshi Inoue,1 Nobuyuki Mitsui,1 Shin Nakagawa,1 Rie Kameyama,1 Yoshiyuki Hayashishita,1 Tohru Shiga,2 Ichiro Kusumi,1 Tsukasa Koyama1 1Department of Psychiatry, Graduate School of Medicine, Hokkaido University, Sapporo, Japan ...
Kitaichi Y   +8 more
doaj  

An example of a misnomer in medicine: Choice of the term basal ganglia for the basal nuclei

open access: yesAnnals of Medical Research, 2020
Zafer Sahin   +2 more
openaire   +2 more sources

Revolutionizing Seborrheic Keratosis Treatment: A Case Report of Successful Topical Treatment of Basal Cell Papilloma Using Siddha Medicine

open access: yesCureus
Seborrheic keratosis (SK), also known as seborrheic warts or basal cell papilloma, is a common benign epidermal tumor typically seen in middle-aged and older adults. SK is one of the most frequently encountered skin lesions by primary care physicians and dermatologists in outpatient settings.
Karan Chand Mohan Singh, Saravanasingh   +3 more
openaire   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

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