Results 81 to 90 of about 938,616 (362)
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Hypoadrenocorticism in an aged cat [PDF]
A 13-year-old, female, neutered, domestic longhair cat was referred to the hospital with a two-month history of fluctuating weakness, lethargy, inappetence and intermittently soft stools.
Fowlie, Samuel J.+2 more
core +1 more source
Pigmented basal cell carcinoma of the eyelid in Hispanics
Lily Koo Lin1, Han Lee2, Eli Chang11Department of Oculoplastics, Doheny Eye Institute, Los Angeles, CA, USA; 2Department of Dermatology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USABackground: Pigmented basal ...
Lily Koo Lin, Han Lee, Eli Chang
doaj
Eva Krishna Sutedja, Ghabrina Saraswati Elgianda, Endang Sutedja, Kartika Ruchiatan Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin Hospital, Bandung, IndonesiaCorrespondence: Eva Krishna Sutedja,
Sutedja EK+3 more
doaj
A incidência do carcinoma basocelular vem aumentando em todos os países. Realizou-se estudo ecológico de 5169 laudos de carcinoma basocelular, da FMB-Unesp, entre janeiro/1999 e dezembro/2009. O incremento médio da incidência para o período foi de 90,6%,
Juliano Vilaverde Schmitt+3 more
doaj +1 more source
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter+8 more
wiley +1 more source
Editorial: Community series in adaptor molecules in T cell signaling, volume II
Sutatip Pongcharoen+2 more
doaj +1 more source
Bilateral Basal Ganglia Calcification: The Etiology and Clinical Findings of 17 Patients
OBJECTIVE: Bilateral basal ganglia calcification is a rare disease with symmetrical and bilateral deposition of calcium and other minerals in the basal ganglia, cerebellum, dentate nucleus, and white matter. Clinical findings are variable and can present
Aylin Akçalı+2 more
doaj
Milena Taskovska,1 Maja Frelih,2 Tomaž Smrkolj,1 Metka Volavšek2 1Chair of Surgery, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 2Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana ...
Taskovska M+3 more
doaj
This study was conducted at the poultry farm ,Veterinary Public Health .,College of Veterinary Medicine, to study the effect of Tumeric (Curcuma longa) on broiler performance and some physiological traits .Two hundred fifty day-old (Rose308) broiler ...
Raghdad A. Abd Al-Jaleel
doaj +1 more source