Results 131 to 140 of about 645,299 (299)

Individual response in body mass and basal metabolism to the risks of predation and starvation in passerines.

J Exp Biol, 2023
Broggi J, Nilsson JÅ.
europepmc   +1 more source

Tonic TCR Signaling Inversely Regulates the Basal Metabolism of CD4⁺ T Cells. [PDF]

Immunohorizons, 2020
Milam AAV, Bartleson JM, Buck MD, Chang CH, Sergushichev A, Donermeyer DL, Lam WY, Pearce EL, Artyomov MN, Allen PM.   +9 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

ENERGY AND PROTEIN REQUIREMENTS OF GROWING PELIBUEY SHEEP UNDER TROPICAL CONDITIONS ESTIMATED FROM A LITERATURE DATABASE ANALYSES

Tropical and Subtropical Agroecosystems, 2012
Data from previous studies were used to estimate the metabolizable energy and protein requirements for maintenance and growth and basal metabolism energy requirement of male Pelibuey sheep under tropical conditions were estimated. In addition, empty body
Fernando Duarte, Carlos A. Sandoval Castro, Luis A. Sarmiento Franco, Luis O. Tedeschi, Ronald H. Santos-Ricalde   +4 more
doaj  

Studies on the Basal Metabolism of Infants

Eiyo To Shokuryo, 1956
The basal metabolic rate of 21 Japanese infants (2-4 years of age) was measured 3-5 times over in each season for a year by the helmet-mask method, and the seasonal changes of those were as follows:(1) The basal metabolic rate of infants was the lowest in summer and the highest in winter, that of boys in winter was increased by 13.1%, in spring, +8.5%,
openaire   +4 more sources

RpoN1 and RpoN2 play different regulatory roles in virulence traits, flagellar biosynthesis, and basal metabolism in Xanthomonas campestris. [PDF]

Mol Plant Pathol, 2020
Li K, Wu G, Liao Y, Zeng Q, Wang H, Liu F.   +5 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation [PDF]

, 2014
Andersen, MR, Fan, Y, Jimenez del Val, I, Kontoravdi, C, Muller, C, Rasmussen, SK, Sen, JW, Weilguny, D   +7 more
core   +1 more source