Results 281 to 290 of about 22,376,002 (349)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Evolutive acid-base derangements in critically ill patients: epidemiological aspects, association with mortality and metabolic acidosis prediction. [PDF]

Crit Care Sci
Faria CC, Paiva CLN, Araujo LMA, Cardozo Júnior LCM, Park M.   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Base barrier cells provide compartmentalization of choroid plexus, brain and CSF. [PDF]

Nat Neurosci
Verhaege D, De Nolf C, Van Acker L, Claeys W, Castelein J, Van Wonterghem E, Van Imschoot G, Dujardin P, De Spiegelaere W, Hoste E, Boone F, Lidov HGW, Dani N, Derk J, Kremer A, Van Hamme E, Borghgraef P, Lippens S, Lehtinen MK, Siegenthaler J, Van Hoecke L, Vandenbroucke RE.   +21 more
europepmc   +1 more source

Recognition of Non-standard Base Pairs by Triplex-Forming Oligonucleotides Containing an Expanded Genetic Alphabet

Rusling D, Brazzill M, Ma R, Munn K, Prestifilippo L, Pickford A, Kim H, Chen C, Hoshika S, Benner S.   +9 more
europepmc   +1 more source

KNLR: A heterogeneous ensemble learner for predicting Foie gras weight grade in mule ducks (Anas platyrhynchos × Cairina moschata). [PDF]

Poult Sci
Li JC, Mabrouk I, Liu QY, Li SY, Ma XM, Song YP, Ma JY, Zhou YX, Shao JH, Li XY, Wang JB, Xue GZ, Pan HX, Xu J, Hua GQ, Zhang JL, Zhang J, Min W, Zhang FJ, Ma YW, Shi H, Sun YF.   +21 more
europepmc   +1 more source

Omega Nucleic Acids (ΩNA), Ultimate Nucleic Acids for Future Technology. [PDF]

Molecules
Hamada S, Murayama K, Takezawa Y, Toyoda R, Kuzuya A.   +4 more
europepmc   +1 more source

The anatomy of a jackstone: a novel morphometric analysis of a rare urinary calculus. [PDF]

Urolithiasis
Mashiach D, Singh S, Anjum M, Polivka A, Alnajjar R, Wang L, Lee P, Szurmant H, Fricano E.   +8 more
europepmc   +1 more source