Results 101 to 110 of about 179,719,498 (240)

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

open access: yesAdvanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati   +10 more
wiley   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

open access: yesAdvanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou   +10 more
wiley   +1 more source

Base of niche in the Queen's chamber, Great Pyramid [transparency] /

open access: yes
Title from label on top edge of lantern slide.; Part of the Australian Inland Mission collection.; Condition: Good.; "Trade mark ; Photos of the Gt. Pyramid ; 14" -- Printed at top of slide.; Also available in an electronic version via the Internet at ...
Smyth, C. Piazzi (Charles Piazzi), 1819-1900.
core  

Kirigami‐Cut Pattern Designs for the Enhancement of Sensing Performance Induced by Programmable Out‐of‐Plane Deformation

open access: yesAdvanced Science, EarlyView.
Different kirigami patterns are proposed and the parameters are optimized by comparing the out‐of‐plane deformation behavior. Then, the proposed patterns are fabricated on PVDF film using laser technology. The deformed kirigami‐cut PVDF is embedded into PDMS to construct pressure senor.
Xiaodong Huang   +6 more
wiley   +1 more source

Isomeric Ag14 Nanoclusters With Distinct Photophysical and Nanomechanical Properties

open access: yesAdvanced Science, EarlyView.
Ligand‐shell isomerism in atomically precise Ag14 nanoclusters is demonstrated to regulate core distortion, photoluminescence, and mechanical properties. Subtle changes in phosphine ligand arrangement drive a pronounced emission shift from green to red and alter crystal rigidity, revealing a direct structure‐property correlation that offers new design ...
Vivek Yadav   +14 more
wiley   +1 more source

Innovating to increase access to diabetes care in Kenya: an evaluation of Novo Nordisk's base of the pyramid project. [PDF]

open access: yesGlob Health Action, 2019
Shannon GD   +4 more
europepmc   +1 more source

Synchronized Imaging of Hydrogen Peroxide and Hydroxyl Radical in Pyroptosis and Epilepsy

open access: yesAdvanced Science, EarlyView.
A dual‐responsive fluorescent probe, HH, enables synchronized visualization of H2O2 and •OH through spectrally resolved green and red channels. By tracking redox dynamics in pyroptosis and epilepsy models, HH reveals ROS elevation during seizure‐like pathology and supports evaluation of antioxidant and antiepileptic therapeutic interventions.
Yabing Gan   +9 more
wiley   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

open access: yesAdvanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan   +11 more
wiley   +1 more source

Poverty Reduction for Profit? A Critical Examination of Business Opportunities at the Bottom of the Pyramid [PDF]

open access: yes
Leading management thinker C.K. Prahalad argues that selling consumer goods to four billion poor people at the bottom of the economic pyramid (BoP) both generates sizeable profits for large businesses and eliminates poverty.
Jean-Louis Warnholz (QEH)
core  

THE HOUSING FIRST - PROGRAM ACTING FOR BOP DESIGN

open access: yesMix Sustentável
This article explores the social aspect of Sustainable Design and investigates the potential of implementing the Housing First (HF) philosophy as public policy. The HF philosophy is a form of Design for the Base of the Pyramid (BoP) that aims to include
Isabela Macário Custódio   +2 more
doaj  

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