Results 161 to 170 of about 182,670 (299)

Social BusinessesandAfrica’s Base of the Pyramid Market

In a world where Africa’s GDP is projected to grow at 3.5% in 2025 (AfDB African Economic Outlook), the continent paradoxically remains home to over 400 million people living under the poverty line, most of whom form the Base of the Pyramid (BoP). Meanwhile, the African Continental Free Trade Area (AfCFTA), hailed as the world’s largest free trade zone
openaire   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Development of a 3D Printing Liquid Crystal Display (LCD)-Assisted Micromolding Methodology for Custom Fabrication of Polymeric Microneedles Using Experimental Design. [PDF]

Pharmaceutics
Antonara L, Rekkas DM, Pippa N, Dallas PP.   +3 more
europepmc   +1 more source

Enhanced Bandgap Flexibility in Perovskite‐Silicon Tandem Solar Cells via Three‐Terminal Architecture

Advanced Science, EarlyView.
Three‐terminal (3T) perovskite/silicon tandem solar cells overcome the current‐matching constraints of 2T designs. Using an IBC POLO silicon bottom cell, we demonstrate a 30.1% PCE, with performance largely decoupled from perovskite bandgap and enhanced resilience under realistic, time‐dependent solar spectra.
Mohammad Gholipoor, Michael Rienaecker, Xuzheng Liu, Seyedamir Orooji, Lingyi Fang, Paul Fassl, Renjun Guo, Uli Lemmer, Robby Peibst, Ulrich Wilhelm Paetzold   +9 more
wiley   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Pyramid urethral mobilisation hypospadias repair for distal variant: experience with 70 cases. [PDF]

Front Pediatr
Andriescu M, Stanciu O, Stoicescu I, Balanescu L, Balanescu R.   +4 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Lateral swing flap of the nasal pyramid: A novel approach to the anterior skull base and review of surgical approaches. [PDF]

Medicine (Baltimore)
Azar A, Alkheder A, Mustafa A.
europepmc   +1 more source

Harnessing Transformation of Metal‐Ligand Coordination in Dinuclear Ni(II)‐Schiff Base Coordination Polymer for Promoting Electrochemical Oxygen Evolution

Advanced Science, EarlyView.
Ni–Schiff base coordination polymer [Ni2(tmd)2]n was synthesized and applied to enhance alkaline OER by virtue of its transformation between 5‐ and 6‐coordinate Ni sites along with the spin state exchange. ABSTRACT One of the major challenges in overall water splitting is improving the sluggish kinetics of the anodic oxygen evolution reaction (OER ...
Ruei‐Hung Juang, Han‐Jung Li, Yu‐Chung Chang, Chieh‐Wei Chang, Ricky Yu‐Syun Fan, Kien Voon Kong, Jeng‐Lung Chen, Chia‐Shuo Hsu, Po‐Heng Lin, Chun‐Hong Kuo   +9 more
wiley   +1 more source

Geometry-Dependent Photonic Nanojet Formation and Arrays Coupling. [PDF]

Nanomaterials (Basel)
Sun Z, Ge S, Shen L, Li J, Xu S, Zhang J, Xi Y, Liu W.   +7 more
europepmc   +1 more source