Results 161 to 170 of about 179,719,498 (240)

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

open access: yesAdvanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li   +12 more
wiley   +1 more source

The north-west socket-hole of the Great Pyramid [transparency] /

open access: yes
Title from label on top edge of lantern slide.; Part of the Australian Inland Mission collection.; Condition: Slightly cracked.; "Trade mark ; Photos of the Gt.
Smyth, C. Piazzi (Charles Piazzi), 1819-1900.
core  

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee   +3 more
wiley   +1 more source

The northern or entrance face of the Great Pyramid [transparency] /

open access: yes
Title from label on top edge of lantern slide.; Part of the Australian Inland Mission collection.; Condition: Good.; "Trade mark ; Photos of the Gt. Pyramid ; 32" -- Printed at top of slide.; Also available in an electronic version via the Internet at ...
Smyth, C. Piazzi (Charles Piazzi), 1819-1900.
core  

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

open access: yesAdvanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han   +11 more
wiley   +1 more source

The eastern and northern faces of the Great Pyramid [transparency] /

open access: yes
Title from label on top edge of lantern slide.; Part of the Australian Inland Mission collection.; Condition: Good.; "Trade mark ; Photos of the Gt. Pyramid ; 31" -- Printed at top of slide.; Also available in an electronic version via the Internet at ...
Smyth, C. Piazzi (Charles Piazzi), 1819-1900.
core  

Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management

open access: yesAdvanced Science, EarlyView.
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao   +9 more
wiley   +1 more source

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