Results 21 to 30 of about 16,728 (257)

The BipBop programme: Providing access to reliable, affordable and clean energy with a combined approach of investment, offers and training

Field Actions Science Reports, 2012
Universal access to clean energy is a major worldwide concern which has been reaffirmed when 2012 was declared by the United Nations as the International Year of Sustainable Energy for All.
Gilles Vermot Desroches, Thomas André
doaj   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

A emergência da tecnologia social: revisitando o movimento da tecnologia apropriada como estratégia de desenvolvimento sustentável The emergence of social technology: revisiting the appropriate technology movement as a strategy for sustainable development

Revista de Administração Pública, 2008
Este artigo discute os conceitos concernentes à tecnologia social num mundo globalizado, em contraposição às propostas que defendem a adoção, pelas multinacionais, de estratégias organizacionais focadas na base da pirâmide social.
Ivete Rodrigues, José Carlos Barbieri
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Single-Point Incremental Micro-Forming of Thin Shell Products Utilizing High Formability

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
This paper describes single-point incremental micro-forming of miniature shell products 50 µm to 1000 µm in size. First, the conditions of the micro-forming of a pyramid with a 1 mm square base were optimized to cause large elongation of a ...
Toshiyuki OBIKAWA, Tomomi HAKUTANI, Tsutomu SEKINE, Shogo NUMAJIRI, Takashi MATSUMURA, Masahiko YOSHINO   +5 more
doaj   +1 more source

Value supply chains at the base of the pyramid: studies of past and present textile networks [PDF]

Journal of Humanitarian Logistics and Supply Chain Management, 2017
Purpose – Billions of entrepreneurs at the Base of the Pyramid (BoP) operate as small-scale producers within multi-tiered supply chain networks. Unfortunately, a majority of these entrepreneurs are simply unable to derive sufficient value from the ...
Sameer Prasad, James Jaffe, Kuntal Bhattacharyya, Jasmine Tata, Donna Marshall   +4 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Consumption Characteristics Mapping of the Base of the Pyramid (BOP) Population in Brazil

Emerging Markets Journal, 2015
The objective of this study is to outline a diagnosis of the BoP's population in Brazil, regarding their size and consumption characteristics. This is a relevant and current issue, considering that BoP needs to be understood as a large potential market ...
Renata Giovinazzo Spers, James Terence Coulter Wright   +1 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source