Results 51 to 60 of about 182,670 (299)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

The entry of multinational companies to the base of the pyramid: A network perspective [PDF]

open access: yes, 2013
Multinational corporations (MNCs) have traditionally ignored low-income markets, usually referred to as the base of the pyramid (BOP). Despite the dominant poverty in this market, a growing number of MNCs are attempting to learn about successful ...
Tasavori, M
core  

Pyramidal Structures on Yttria‐Stabilized Zirconia after High Temperature Exposure at 1500°C: New Features on an Old Material

open access: yesAdvanced Engineering Materials, EarlyView.
New features on yttria‐stabilized zirconia after exposure at 1500°C: Newly discovered pyramidal structures on an old material. After exposure at 1550°C on the cross section of YSZ new features, namely pyramidal structures are discovered. These structures grow with time, increase in numbers, appear as singularities, are often arranged in strings, and ...
Doris Sebold   +2 more
wiley   +1 more source

Challenges and opportunities of the last mile for the base of the pyramid: the case of Brazil

open access: yesField Actions Science Reports, 2014
The last mile in distribution offers many challenges for organizations to access the Base of the Pyramid (BoP) market. This paper analyses how companies in Brazil are managing to effectively serve these markets.
Edgard Barki, Juracy Parente
doaj  

Lateral Fractal Formation by Crystallographic Silicon Micromachining

open access: yesFractal and Fractional, 2023
A novel wafer-scale silicon fractal fabrication method is presented here for forming pyramids only in the lateral direction using the crystal orientation of silicon. Fractals are fabricated in silicon by masking only the corners (corner lithography) of a
Lucas Johannes Kooijman   +3 more
doaj   +1 more source

Mechanical Properties of Architected Polymer Lattice Materials: A Comparative Study of Additive Manufacturing and CAD Using FEM and µ‐CT

open access: yesAdvanced Functional Materials, EarlyView.
This study examines how pore shape and manufacturing‐induced deviations affect the mechanical properties of 3D‐printed lattice materials with constant porosity. Combining µ‐CT analysis, FEM, and compression testing, the authors show that structural imperfections reduce stiffness and strength, while bulk material inhomogeneities probably enhance ...
Oliver Walker   +5 more
wiley   +1 more source

The Effect of Incubation near an Inversely Oriented Square Pyramidal Structure on Adsorption Properties of Horseradish Peroxidase

open access: yesApplied Sciences, 2022
The incubation of a solution of horseradish peroxidase (HRP) enzyme either below the apex or near the base of an inversely oriented square pyramid (inverted square pyramid; ISP) has been found to influence the enzyme’s aggregation and adsorption ...
Yuri D. Ivanov   +11 more
doaj   +1 more source

Securities Regulation: Opportunities exist for IIROC to regulate responsively [PDF]

open access: yes, 2015
This article examines the applicability of responsive regulation within an inter-agency framework in the financial sector. To do so, the article uses the self-regulatory organization that is responsible for governing Canada’s investment dealers and ...
Jakobsen, Kaj Bjarne   +3 more
core   +3 more sources

Golden‐Ratio–Guided Aperiodic Architected Metamaterials with Simultaneously Enhanced Strength and Toughness

open access: yesAdvanced Functional Materials, EarlyView.
Guided by the golden ratio, a class of aperiodic architected metamaterials is introduced to address the intrinsic trade‐off between strength and toughness. By unifying local geometric heterogeneity with global order, the golden‐ratio‐guided aperiodic architecture promotes spatial delocalization of damage tolerence regions, leading to more tortuous ...
Junjie Deng   +9 more
wiley   +1 more source

Servant leadership, trust and implications for the “Base-of-the-Pyramid” segment in South Africa

open access: yesSouth African Journal of Business Management, 2011
This paper examines the relationship between servant leadership and interpersonal trust in South Africa. The results of this empirical investigation, conducted among low level employees and their managers, revealed a statistically significant ...
A. Chatbury, D. Beaty, H. S. Kriek
doaj   +1 more source

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