Results 111 to 120 of about 1,859,090 (336)
Cooperative base pair melting by helicase and polymerase positioned one nucleotide from each other
eLife, 2015 Leading strand DNA synthesis requires functional coupling between replicative helicase and DNA polymerase (DNAP) enzymes, but the structural and mechanistic basis of coupling is poorly understood.
Divya Nandakumar +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2018 Förster resonance energy transfer (FRET) between a donor nucleobase analogue and an acceptor nucleobase analogue, base–base FRET, works as a spectroscopic ruler and protractor.
Mattias Bood +4 more
doaj +1 more source
Frontiers in Plant Science, 2016 Gene expression is mediated through interaction between cis regulatory elements and its cognate transcription factors. Cis regulatory elements are defined as non-coding DNA sequences that provide the binding sites for transcription factors and are ...
Rajesh eMehrotra +4 more
doaj +1 more source
, 1992 A device for holding reading materials for use by readers without arm mobility is presented. The device is adapted to hold the reading materials in position for reading with the pages displayed to enable turning by use of a rubber tipped stick that is ...
Eklund, Wayne D., Kerley, James J.
core +1 more source
Distribution of Primes and of Interval Prime Pairs Based on $Θ$ Function [PDF]
, 2010 Yifang Fan, Zhiyu Li
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
, 2014 Citation: 'base pairing' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.B00607 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
High temperature penetrator assembly with bayonet plug and ramp-activated lock [PDF]
, 1982 A penetration apparatus, for very high temperature applications in which a base plug is inserted into an opening through a bulkhead is described. The base plug has a head shape and is seated against the highest temperature surface of the bulkhead, which ...
Wood, K. E.
core +1 more source