Results 201 to 210 of about 446,496 (303)

Parallel Evolution at the Regulatory Base-Pair Level Contributes to Mammalian Interspecific Differences in Polygenic Traits. [PDF]

Mol Biol Evol
Okamoto AS, Capellini TD.
europepmc   +1 more source

ΩqPCR measures telomere length from single-cells in base pair units. [PDF]

Nucleic Acids Res, 2021
Xiong F, Frasch WD.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Hydration Waters Make Up for the Missing Third Hydrogen Bond in the A·T Base Pair. [PDF]

ACS Phys Chem Au
Mak CH.
europepmc   +1 more source

Referee report. For: Matched molecular pair-based data sets for computer-aided medicinal chemistry [v2; indexed, http://f1000r.es/309]

, 2014
P. T. Walters
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A single base pair substitution in zebrafish distinguishes between innate and acute startle behavior regulation. [PDF]

PLoS One
Ortiz EA, Campbell PD, Nelson JC, Granato M.   +3 more
europepmc   +1 more source

Crystal Structure of an RluF–RNA Complex: A Base-Pair Rearrangement Is the Key to Selectivity of RluF for U2604 of the Ribosome

, 2009
Akram Alian, Andrew DeGiovanni, Sarah L. Griner, Janet Finer-Moore, Robert M. Stroud   +4 more
openalex   +1 more source

Homozygosity for a single base-pair mutation in the oocyte-specific GDF9 gene results in sterility in Thoka sheep [PDF]

, 2009
Linda Nicol, Stephen Bishop, Ricardo Pong‐Wong, Christian Bendixen, Lars‐Erik Holm, S. M. Rhind, Alan S. McNeilly   +6 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source