Results 141 to 150 of about 353,589 (332)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

6-Pyrazolylpurine and its deaza derivatives as nucleobases for silver(I)-mediated base pairing with pyrimidines. [PDF]

J Biol Inorg Chem, 2023
Escher D, Schäfer T, Hebenbrock M, Müller J.   +3 more
europepmc   +1 more source

Coexisting Oscillations, Heterogeneous Multistability and Multi-Scroll Chaos in a Pair of Coupled Memristor-Based Duffing Oscillators

, 2022
Ouzerou Mouncherou Njimah, R. Janarthanan, Jacques Kengne, Adélaïde Nicole Kengnou Telem   +3 more
openalex   +1 more source

Avoiding incompatible drug pairs in central-venous catheters of patients receiving critical care: an algorithm-based analysis and a staff survey [PDF]

, 2023
Leonhardt Alexander Fabian Wagner, Martina Patrizia Neininger, Jlm Jan Hensen, Olaf Zube, Thilo Bertsche   +4 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Structural analysis of base mispairing in DNA containing oxidative guanine lesion

Open Physics, 2007
Fujimoto Hirofumi, Pinak Miroslav, Nemoto Toshiyuki, Bunta Juraj   +3 more
doaj   +1 more source

Unveiling the solution structure of a DNA duplex with continuous silver-modified Watson-Crick base pairs

Nature Communications
The challenge of transforming organized DNA structures into their metallized counterparts persists in the scientific field. In this context, utilizing DNA molecules modified with 7-deazapurine, provides a transformative solution.
Uroš Javornik, Antonio Pérez-Romero, Carmen López-Chamorro, Rachelle M. Smith, José A. Dobado, Oscar Palacios, Mrinal K. Bera, May Nyman, Janez Plavec, Miguel A. Galindo   +9 more
doaj   +1 more source

In vivo-like nearest neighbor parameters improve prediction of fractional RNA base-pairing in cells. [PDF]

Nucleic Acids Res, 2023
Sieg JP, Jolley EA, Huot MJ, Babitzke P, Bevilacqua PC.   +4 more
europepmc   +1 more source

A Corpus-Based Approach to the Vocabulary Teaching and Learning—Implications From the Corpus-Based Collocational Research on Two Pairs of Synonyms [PDF]

, 2015
Yanhui Chen
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source