Results 181 to 190 of about 353,589 (332)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Activation of bacterial transcription by distortion of promoter base pairing. [PDF]

open access: yesNucleic Acids Res
Klimova KM   +4 more
europepmc   +1 more source

Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16. [PDF]

open access: yesLife Sci Alliance, 2022
Quéméner AM   +11 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

DNA-Mimicking Metal-Organic Frameworks with Accessible Adenine Faces for Complementary Base Pairing. [PDF]

open access: yesJACS Au, 2022
Chand S   +8 more
europepmc   +1 more source

Ultranodal pair states in iron-based superconductors [PDF]

open access: green, 2019
Chandan Setty   +3 more
openalex  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Enhanced microRNA accumulation and gene silencing efficiency through optimized precursor base pairing. [PDF]

open access: yesPlant J
Llorens-Gámez JJ   +5 more
europepmc   +1 more source

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