Results 301 to 310 of about 32,528,266 (371)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee +7 more
wiley +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
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Bioinform., 2021
MOTIVATION The recent discovery of numerous non-coding RNAs (long non-coding RNAs, in particular) has transformed our perception about the roles of RNAs in living organisms.
Jaswinder Singh +5 more
semanticscholar +1 more source
MOTIVATION The recent discovery of numerous non-coding RNAs (long non-coding RNAs, in particular) has transformed our perception about the roles of RNAs in living organisms.
Jaswinder Singh +5 more
semanticscholar +1 more source
Angewandte Chemie International Edition, 2007
AbstractRecent developments show encouraging results for the use of DNA as a construction material for nanometer‐sized objects. Today, however, DNA‐based molecular nanoarchitectures are constructed with mainly unmodified or at best end‐modified oligonucleotides, thus shifting the development of functionalized DNA structures into the limelight.
Guido H, Clever +2 more
openaire +2 more sources
AbstractRecent developments show encouraging results for the use of DNA as a construction material for nanometer‐sized objects. Today, however, DNA‐based molecular nanoarchitectures are constructed with mainly unmodified or at best end‐modified oligonucleotides, thus shifting the development of functionalized DNA structures into the limelight.
Guido H, Clever +2 more
openaire +2 more sources
Small, 2018
Controlled drug release systems can enhance the safety and availability but avoid the side effect of drugs. Herein, the concept of DNA complementary base pairing rules in biology is used to design and prepare a photothermal-triggered drug release system.
Qichen Zhan +4 more
semanticscholar +1 more source
Controlled drug release systems can enhance the safety and availability but avoid the side effect of drugs. Herein, the concept of DNA complementary base pairing rules in biology is used to design and prepare a photothermal-triggered drug release system.
Qichen Zhan +4 more
semanticscholar +1 more source
Pairing-Based Cryptography – Pairing 2012
2013This book constitutes the refereed proceedings of the 5th International Conference on Pairing-Based Cryptography, Pairing 2012, held in Cologne, Germany, in May 2012. The 17 full papers for presentation at the academic track and 3 full papers for presentation at the industrial track were carefully reviewed and selected from 49 submissions. These papers
Abdalla, Michel, Lange, Tanja
openaire +3 more sources
Stable Copper(I)-Mediated Base Pairing in DNA.
Angewandte Chemie, 2018A GNA (glycol nucleic acid) functionalized nucleoside analogue containing the artificial nucleobase 1H-imidazo[4,5-f][1,10]phenanthroline (P) was used to form a copper(I)-mediated base pair within a DNA duplex.
B. Jash, Jens Müller
semanticscholar +1 more source
2005
Chapter 23 showed us how to build DL systems on the Jacobian of curves. In Chapter 1 we introduced DL systems with bilinear structure. In this chapter we first give more applications of this construction, namely the extension of the tripartite protocol given before to multiparty key exchange, identity-based cryptography, and short signatures. In recent
Duquesne, S., Lange, T.
openaire +1 more source
Chapter 23 showed us how to build DL systems on the Jacobian of curves. In Chapter 1 we introduced DL systems with bilinear structure. In this chapter we first give more applications of this construction, namely the extension of the tripartite protocol given before to multiparty key exchange, identity-based cryptography, and short signatures. In recent
Duquesne, S., Lange, T.
openaire +1 more source
Journal of Biomolecular Structure and Dynamics, 1996
Three-dimensional structures of a representative set of more than 30 hydrogen-bonded nucleic acids pairs have been studied by reliable ab initio quantum mechanical methods. We show that many hydrogen-bonded nucleic acid base pairs are intrinsically nonplanar, mainly due to the partial sp3 hybridization of nitrogen atoms of their amino groups and ...
J, Sponer +3 more
openaire +2 more sources
Three-dimensional structures of a representative set of more than 30 hydrogen-bonded nucleic acids pairs have been studied by reliable ab initio quantum mechanical methods. We show that many hydrogen-bonded nucleic acid base pairs are intrinsically nonplanar, mainly due to the partial sp3 hybridization of nitrogen atoms of their amino groups and ...
J, Sponer +3 more
openaire +2 more sources