Results 131 to 140 of about 20,204 (286)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Base Rate Neglect in Linguistic Category Learning
This paper presents a categorization experiment supporting the hypothesis that base-rate-neglect occurs in linguistic category learning (and, thus, is a cross-domain phenomenon), and that it is more likely for those learners who engage in explicit problem-solving, rather than implicit learning.
Pertsova, Katya +3 more
openaire +1 more source
A Bayesian latent-mixture model analysis shows that informative samples reduce base-rate neglect.
, 2014 Guy E. Hawkins +4 more
openalex +2 more sources
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Re-Examining Base-Rate Neglect: The Effect Of Context [PDF]
Classic base-rate neglect studies have been consistently criticised for lacking ecological validity. A study by Welsh & Navarro (2012) found this heuristic was significantly reduced when participants perceived the base rate as more relevant. The present study aims to study this phenomenon through a more realistic scenario while simultaneously ...
Adler, Nine, Dewitt, Stephen H
openaire
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Exploring the inter-factor network of psychological abuse, life-event stress, and suicidal behavior: evidence from Chinese college students. [PDF]
Front PsycholCao J, Huo Z, Liu X, Meng N, Tan T.
europepmc +1 more source