Results 131 to 140 of about 965,609 (309)

Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK [PDF]

open access: yes, 1995
The sequence variation in a 934 base-pair region of the gene encoding the haemagglutinin-neuraminidase of five human parainfluenza virus type 3 (HPIV3) isolates was determined together with that of a prototype UK strain. All of the clinical isolates were
Easton, A. J. (Andrew J.)   +1 more
core   +1 more source

Sequence-encoded intermolecular base pairing modulates fluidity in DNA and RNA condensates

open access: yesNature Communications
Nature uses bottom-up self-assembly to build structures with remarkable complexity and functionality. Understanding how molecular-scale interactions translate to macroscopic properties remains a major challenge and requires systems that effectively ...
Sumit Majumder   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Utilising Uracil DNA Glycosylase to detect the presence of 5-Methylcytosine [PDF]

open access: yes, 2014
DNA is regularly subjected to endogenous and exogenous reagents that cause mutations that can be detrimental to a cell if they are not repaired. One class of enzymes responsible for DNA repair is the family of DNA glycosylases and their role is to remove
Kimber, Scott T.
core  

Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain WSM1325, an effective microsymbiont of annual Mediterranean clovers [PDF]

open access: yes, 2010
Rhizobium leguminosarum bv trifolii is a soil-inhabiting bacterium that has the capacity to be an effective nitrogen fixing microsymbiont of a diverse range of annual Trifolium (clover) species.
Alex Copeland   +69 more
core   +2 more sources

Vertical Ground-Motion Effects in Base-Isolated Buildings: Preliminary Observations from Twin Fixed-Base and Base-Isolated Structures During the 18 March 2025 Potenza Sequence

open access: yesBuildings
On 18 March 2025, a moderate earthquake with moment magnitude Mw 4.2 struck the Basilicata region in Southern Italy. The event occurred at 09:01:25 UTC with an epicentre located approximately 4 km northeast of the city of Potenza (PZ). The earthquake was
Rocco Ditommaso, Felice Carlo Ponzo
doaj   +1 more source

A Bassline Generation System Based on Sequence-to-Sequence Learning

open access: yes, 2019
This paper presents a detailed explanation of a system generating basslines that are stylistically and rhythmically interlocked with a provided audio drum loop. The proposed system is based on a natural language processing technique: word-based sequence-to-sequence learning using LSTM units.
Behzad Haki, Sergi Jordà
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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