Results 351 to 360 of about 31,885,483 (388)
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Consistency of Sequence-Based Gene Clusters
Journal of Computational Biology, 2010In comparative genomics, differences or similarities of gene orders are determined to predict functional relations of genes or phylogenetic relations of genomes. For this purpose, various combinatorial models can be used to specify gene clusters--groups of genes that are co-located in a set of genomes.
Wittler, Roland +3 more
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Journal of Molecular Biology, 1964
Nucleotide sequences have been studied in pancreatic RNase digests of soluble RNA. Various sequences containing “odd” nucleotides have been identified. The finding of sequences with more than one “odd” nucleotide, such as 2-dimethyl guanyl-5-ribosyl uracil phosphate and 1-methyl guanyl-2-methyl guanyl cytidylic acid, is evidence for a clustering of the
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Nucleotide sequences have been studied in pancreatic RNase digests of soluble RNA. Various sequences containing “odd” nucleotides have been identified. The finding of sequences with more than one “odd” nucleotide, such as 2-dimethyl guanyl-5-ribosyl uracil phosphate and 1-methyl guanyl-2-methyl guanyl cytidylic acid, is evidence for a clustering of the
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Low-energy electron-induced DNA damage: effect of base sequence in oligonucleotide trimers.
Journal of the American Chemical Society, 2010DNA damage induced by low-energy electrons (LEEs) has attracted considerable attention in recent years because LEEs represent a large percentage of the total energy deposited by ionizing radiation and because LEEs have been shown to damage DNA components.
Zejun Li +3 more
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Itemset Based Sequence Classification [PDF]
, 2013 Sequence classification is an important task in data mining. We address the problem of sequence classification using rules composed of interesting itemsets found in a dataset of labelled sequences and accompanying class labels. We measure the interestingness of an itemset in a given class of sequences by combining the cohesion and the support of the ...
Zhou, Cheng, Cule, Boris, Goethals, Bart
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The complete genome sequence of Escherichia coli K-12.
Science, 1997The 4,639,221-base pair sequence of Escherichia coli K-12 is presented. Of 4288 protein-coding genes annotated, 38 percent have no attributed function. Comparison with five other sequenced microbes reveals ubiquitous as well as narrowly distributed gene ...
F. Blattner +16 more
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Skim-Based Genotyping by Sequencing
2014Genotyping by sequencing (GBS) is a relatively new method used to determine the differences in the genetic makeup of individuals. Its novelty stems from a combination of two already available methods: genotyping and next-generation sequencing. Depending on the individual study design GBS protocols can take multiple forms, however most share a sequence ...
David Edwards +3 more
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Position-based sequence weights
Journal of Molecular Biology, 1994Sequence weighting methods have been used to reduce redundancy and emphasize diversity in multiple sequence alignment and searching applications. Each of these methods is based on a notion of distance between a sequence and an ancestral or generalized sequence.
Steven Henikoff, Jorja G. Henikoff
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Pattern Based Sequence Classification
IEEE Transactions on Knowledge and Data Engineering, 2016Sequence classification is an important task in data mining. We address the problem of sequence classification using rules composed of interesting patterns found in a dataset of labelled sequences and accompanying class labels. We measure the interestingness of a pattern in a given class of sequences by combining the cohesion and the support of the ...
Zhou, Cheng, Cule, Boris, Goethals, Bart
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Sequencing-Based Typing of HLA
2007Human leukocyte antigen (HLA) typing is largely performed by use of PCR-based techniques in patients that require stem cell transplantation. In this chapter, HLA typing by sequencing-based typing techniques is described.
A. Salama, Berthold Hoppe
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Base Sequence and Higher-Order Structure Induce the Complex Excited-State Dynamics in DNA
Science, 2008The high photostability of DNA is commonly attributed to efficient radiationless electronic relaxation processes. We used femtosecond time-resolved fluorescence spectroscopy to reveal that the ensuing dynamics are strongly dependent on base sequence and ...
N. Schwalb, F. Temps
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