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Sequence-Based Markers

2015
Marker-assisted selection (MAS) has revolutionized plant and animal breeding activities. MAS is based on DNA markers, which facilitate gene/QTL identification and mapping and gene/QTL transfer, and has many other applications. Some of the important issues concerning marker systems relate to their abundance, genome-wide distribution, cost and effort for
B. D. Singh, A. K. Singh
openaire   +2 more sources

NMR Investigation of the Complexation of Daunomycin with Deoxytetranucleotides of Different Base Sequence in Aqueous Solution

Journal of Biomolecular Structure and Dynamics, 2000
500 MHz NMR spectroscopy has been used to investigate the complexation of the anthracycline antibiotic daunomycin (DAU) with self-complementary deoxytetranucleotides, 5′-d(CGCG), 5′-d(GCGC), 5′-d(TGCA), 5′-d(ACGT) and 5′-d(AGCT), of different base ...
D. Davies   +3 more
semanticscholar   +1 more source

DNA-Based Sequencing Assays

2018
Modern cytopathologists need to incorporate molecular testing into their clinical practice and be able to translate molecular assays into patient care. The detection of genomic alterations may not only refine uncertain morphological diagnoses but may also provide crucial theranostic information.
Pisapia, Pasquale   +4 more
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Sequence-based MicroRNA Clustering

Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies, 2016
MicroRNAs (miRNAs) play important roles in post-transcriptional gene regulation. Altogether, understanding integrative and co-operative activities in gene regulation is conjugated with identification of miRNA families. In current applications, the identification of such groups of miRNAs is only investigated by the projections of their expression ...
Mahinur S. Akkaya   +2 more
openaire   +2 more sources

Reductive electron transfer in phenothiazine-modified DNA is dependent on the base sequence.

Chemistry, 2005
A new DNA assay has been designed, prepared and applied for the chemical investigation of reductive electron transfer through the DNA. It consists of 5-(10-methyl-phenothiazin-3-yl)-2'-deoxyuridine (Ptz-dU, 1) as the photoexcitable electron injector and ...
C. Wagner, H. Wagenknecht
semanticscholar   +1 more source

Base-sequence dependence of noncovalent complex formation and reactivity of benzo[a]pyrene diol epoxide with polynucleotides.

Biochemistry, 1988
The base-sequence selectivity of the noncovalent binding of (+/-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyr ene (BPDE) to a series of synthetic polynucleotides in aqueous solutions (5 mM sodium cacodylate buffer, 20 mM NaCl, pH 7.
N. Geacintov   +4 more
semanticscholar   +1 more source

Consensus sequences based on plurality rule

Bulletin of Mathematical Biology, 1992
We apply concepts of social choice theory, in particular those concerning median and plurality rules, to investigate the problem of finding a consensus of aligned molecular sequences. Our model of consensus permits consensus elements at each aligned position to denote ambiguity codes if several alternatives are equally-preferred candidates for ...
William H. E. Day, Fred R. McMorris
openaire   +3 more sources

Filtering Bio-sequence Based on Sequence Descriptor

2006
Study on biological sequence database similarity searching has received substantial attention in the past decade, especially after the sequencing of the human genome. As a result, with larger and larger increases in database sizes, fast similarity search is becoming an important issue.
Jen-Peng Huang   +2 more
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The Evolution of Base Sequences in Polynucleotides

1965
Publisher Summary This chapter discusses the real problems in the evolution of organisms and the understanding of the evolution at other levels of the organization that suggests comparative examination of the chemical structure of the genes. In addition, these discussions of nucleotide sequence leads to a consideration of a variety of subjects, such ...
openaire   +3 more sources

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