Results 61 to 70 of about 14,483,128 (326)
InAs–InP Superlattice Nanowires with Tunable Phonon Frequencies
Advanced Physics ResearchThe control of heat conduction through the manipulation of phonons in solids is of fundamental interest and can be exploited in applications for thermoelectric conversion. In this context, the advent of novel semiconductor nanomaterials with high surface‐
V. Zannier +8 more
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FGF-21 levels in polyuria-polydipsia syndrome
Endocrine Connections, 2018 The pathomechanism of primary polydipsia is poorly understood. Recent animal data reported a connection between fibroblast growth factor 21 (FGF-21) and elevated fluid intake independently of hormonal control by the hormone arginine-vasopressin (AVP) and
Julie Refardt +8 more
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Gestão do Risco Operacional: Uma Avaliação do Novo Acordo de Capitais - Basiléia II
Revista Contemporânea de Contabilidade, 2006 This study aims to evaluate the advancements in the negotiations of the International Convergence of Capital Measurement and Capital Standards: a Revised Framework - Basel II, in the context of the failure of financial institutions, which highlights the ...
José Matias Pereira
doaj
Provisions and Enhancements Brought by Basel II Agreement [PDF]
Ovidius University Annals: Economic Sciences Series, 2017 The article aims to present the comparison between the core approaches of Basel I and Basel II Agreements, focusing on the impact of regulations upon the management of financial assets portfolio held by banks in a globally diversified environment.
Munteanu Bogdan
doaj
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source
Zum mittelalterlichen Dichter und Philosophen Dante Alighieri (1265–1321) Rezension zu: Monaco, Elisa: Dante und das Gedächtnis. Eine interdisziplinäre Studie. Schwabe Verlag: Basel 2021, 347 S. ISBN 978-37965-4427-9 [PDF]
, 2022 Maria Sass
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DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source