Results 141 to 150 of about 5,534,118 (380)

Implications of Basel II for Latin America [PDF]

open access: yes
Despite delays, Basel II remains set to be finalized this year with implementation in Basel Committee countries by the end of 2006. How will this agreement between a set of G10+ countries affect emerging economies?
Andrew Powell
core  

Value-at-Risk and expected shortfall for rare events [PDF]

open access: yes, 2008
We show that the use of correlations for modeling dependencies may lead to counterintuitive behavior of risk measures, such as Value-at-Risk (VaR) and Expected Short- fall (ES), when the risk of very rare events is assessed via Monte-Carlo techniques ...
Mittnik, Stefan, Yener, Tina
core  

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv   +8 more
wiley   +1 more source

Auswirkungen des Basel II Akkords auf österreichisches KMU [PDF]

open access: yes, 2004
The paper discusses the impact of the Basel II Accord on the financing of small and medium size enterprises (SME) in Austria. Although the Basel II Accord has not been established yet, the study tries to evaluate the expected impact of the Basel II ...
Heimer, Thomas, Köhler, Thomas
core  

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Understanding the Internal Measurement Approach to Assessing Operational Risk Capital [PDF]

open access: yes
The recent publication by the Basel Committee of CP2.5, the working paper on Operational Risk Capital Charges, has shed new light on the methods that will be proposed for the measurement of operational risks in the Basel II Accord.
Carol Alexander
core  

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

open access: yesAdvanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang   +6 more
wiley   +1 more source

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