The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer
Advanced Science, EarlyView.In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu +16 more
wiley +1 more source
The Behaviours of Electromagnetic Wave Propagation in Carbon Nanotube-Layered Nanocomposites. [PDF]
Materials (Basel)Basmaci AN, Filiz S.
europepmc +1 more source
Advanced Science, EarlyView.BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou +9 more
wiley +1 more source
Türkiye`de Basel uygulamaları ve Basel III çerçevesinde Türk finansal sistemi
, 2020 In Turkey and the world economic crisis occurs. The 1929 Economic Crisis and the 1973 Oil Crisis influenced the banking sector of the countries, leading to bankruptcy. The crisis and bankruptcy of the banks led the banking sector to create an institution that will bring common standards and regulations.
openaire +2 more sources
Advanced Science, EarlyView.A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim +4 more
wiley +1 more source
Correction: Dhillon et al. Molecular Insights and Therapeutic Advances in Low-Risk Myelodysplastic Neoplasms: A Clinical Review. <i>Cancers</i> 2025, <i>17</i>, 3610. [PDF]
Cancers (Basel)Dhillon V +2 more
europepmc +1 more source
HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration
Advanced Science, EarlyView.This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong +14 more
wiley +1 more source
Correction: López-Paterna et al. Quality of Life, Perceived Social Support, and Treatment Adherence Among Methadone Maintenance Program Users: An Observational Cross-Sectional Study. <i>Healthcare</i> 2025, <i>13</i>, 1849. [PDF]
Healthcare (Basel)López-Paterna P +4 more
europepmc +1 more source