Results 221 to 230 of about 239,330 (291)

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

open access: yesDrug Testing and Analysis, EarlyView.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp   +6 more
wiley   +1 more source

In Vitro Metabolism of Δ8‐, Δ9‐, and Δ10‐THC in Human Hepatocytes: Distinct Δ10‐THC Biotransformation and Implications for Drug Testing

open access: yesDrug Testing and Analysis, EarlyView.
Δ8‐THC and Δ9‐THC showed comparable metabolic profiles. In contrast, Δ10‐THC underwent extensive glucuronidation and hydroxylation, with only minor formation of a carboxy metabolite, indicating a markedly different metabolic pathway. These differences may increase the risk of misidentification and misinterpretation in cannabis drug testing.
Robert Kronstrand   +4 more
wiley   +1 more source

Impact of concomitant left-sided valve disease on outcomes following tricuspid valve transcatheter edge-to-edge repair: insights from EuroTR. [PDF]

open access: yesESC Heart Fail
Gmeiner J   +56 more
europepmc   +1 more source

Faster growing and more functionally diverse: global change alters functional trait composition of mountain plant communities in the European Alps

open access: yesEcography, EarlyView.
Understanding how global change reshapes mountain plant communities is essential for predicting biodiversity and ecosystem function in a warming world. Using resurvey data from over 1400 non‐forest vegetation plots across the European Alps, we show that community‐weighted means of key functional traits capturing important dimensions of plant ecological
Sergey Rosbakh   +2 more
wiley   +1 more source

Enhanced Contribution of Biexciton‐Mediated Decay Kinetics in Perovskite Nanocrystals Via Sequential Ultrafast Excitation

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Sequential ultrafast excitation is shown to increase the relative kinetic weighting of biexciton‐mediated decay in CsPbBr3 nanocrystals without increasing the total excitation fluence. By temporally structuring excitation within the exciton lifetime, the early‐time fast decay contribution becomes more pronounced while the fitted fast decay constants ...
Lijie Wang   +8 more
wiley   +1 more source

Machine learning‐based prediction of elevated N terminal pro brain natriuretic peptide among US general population

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 859-868, April 2025.
Abstract Aims Natriuretic peptide‐based pre‐heart failure screening has been proposed in recent guidelines. However, an effective strategy to identify screening targets from the general population, more than half of which are at risk for heart failure or pre‐heart failure, has not been well established.
Yuichiro Mori   +5 more
wiley   +1 more source

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