Results 21 to 30 of about 158 (133)

A Closed‐Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy

Advanced Science, EarlyView.
The work developed a closed‐loop hybrid discovery system to rationally design and predict high‐performance Type I PSs for hypoxic tumor therapy. 664 Potential candidates are identified from a dataset through a support vector machine (SVM) classification model, and two candidates are experimentally verified as Type I PSs, which highlighted the potential
Xia Ling, Yixin Zhu, Min Li, Zongliang Xie, Lei Cao, Wentao Song, Dandan Wang, Duo Mao, Xiaonan Wang, Bin Liu   +9 more
wiley   +1 more source

Disseny d'ontologia i anàlisi comparatiu de bases de dades semàntiques

, 2013
Introducción a los conceptos básicos de la web semántica, diseño de una ontología original y análisis comparativo de dos almacenes de datos semánticos: VirtuosoDB y OWLIM.
openaire   +2 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Solution‐Processed Organic Photovoltaics: Fabrication Advances and Challenges

Advanced Science, EarlyView.
This review highlights recent advances in organic photovoltaic (OPV) device fabrication, emphasizing how material selection, interface engineering, and scalable processing techniques shape device performance. It discusses progress in photoactive and charge transport layers, electrode optimization, and large‐area manufacturing, offering insights into ...
Kerui Liu, Chenyujie Zhu, Yuanyuan Jiang, Feng Liu, Xiaozhang Zhu   +4 more
wiley   +1 more source

Quantification of Gaseous Products Evolved at Industrially Relevant Current Densities During CO2 Electroreduction and Water Electrolysis Using Online Gas Chromatography

Advanced Energy and Sustainability Research, EarlyView.
The dilution of gaseous products obtained at high‐current densities during CO2 electroreduction or water electrolysis enables their accurate quantification via online gas chromatography, which is crucial for reliable catalyst benchmarking. The corresponding Faradaic efficiencies can then be calculated with low deviations using two different instruments,
Raíssa Ribeiro Lima Machado, Bright Nsolebna Jaato, Torsten Claus Schmidt, Ignacio Sanjuán, Corina Andronescu   +4 more
wiley   +1 more source

Metal‐Mediated Nitrogen Doping of Carbon Supports Boosts Hydrogen Production from Ammonia

Angewandte Chemie, EarlyView.
A virtuous catalytic cycle is established as the carbon support simultaneously tunes electron density and stores atomic nitrogen formed via Ru–N species during ammonia decomposition, resulting in self‐enhancing catalysis. Abstract Ammonia is an attractive hydrogen carrier, yet its practical use is limited by the need for efficient catalytic ...
Thomas J. Liddy, Benjamin J. Young, Emerson C. Kohlrausch, Andreas Weilhard, Gazi N. Aliev, Yifan Chen, Manfred E. Schuster, Mohsen Danaie, Luke L. Keenan, Donato Decarolis, Diego Gianolio, Siqi Wang, Mingming Zhu, Graham J. Hutchings, David M. Grant, Wolfgang Theis, Tien‐Lin Lee, David A. Duncan, Alberto Roldan, Andrei N. Khlobystov, Jesum Alves Fernandes   +20 more
wiley   +2 more sources

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

Unexpected Dual Function of Plant YUCCA Enzymes Links Chlorophyll Catabolism to Auxin Homeostasis

Angewandte Chemie, EarlyView.
YUCCA enzymes are well known to catalyze the main step of auxin biosynthesis in plants. Here, a hitherto undescribed dual function was discovered, revealing that some YUCCAs also act in chlorophyll degradation. In vitro feedback regulation furthermore suggests a link between chlorophyll degradation and hormone homeostasis and a physiological role of ...
Sina Rütschlin, Lei Zhang, Cornelia A. Karg, Michael Zwerger, Johanna M. Gostner, Simone Moser, Robin Teufel   +6 more
wiley   +2 more sources

“Will you be there for me?” Social support from family and friends during cold case sexual assault prosecutions

American Journal of Community Psychology, EarlyView.
Abstract If sexual assault survivors report the assault to the criminal legal system, they often need informal support from family and friends throughout the long and frequently retraumatizing process of investigation and prosecution. This study is part of a long‐term community‐based participatory action research project in a predominately Black ...
Rebecca Campbell, Rachael Goodman‐Williams, Katie Gregory, McKenzie Javorka, Jasmine Engleton   +4 more
wiley   +1 more source

Disseny físic de bases de dades

, 2012
El disseny físic de bases de dades constitueix la quarta etapa en el procés de disseny d’una base de dades. En les etapes anteriors s’ha realitzat l’anàlisi de requeriments, el disseny conceptual i, finalment, el disseny lògic de la base de dades. En aquest mòdul veurem el procés de transformació del model lògic, obtingut en l’etapa anterior, cap a un ...
Cabré Segarra, Blai, Casas Roma, Jordi, Costal Costa, Dolors, Juanola Juanola, Pere, Rius Gavidia, Àngels, Segret Sala, Ramon   +5 more
openaire   +1 more source