Results 11 to 20 of about 5,596 (193)

A Single Nucleotide Polymorphism in the Il17ra Promoter Is Associated with Functional Severity of Ankylosing Spondylitis. [PDF]

PLoS ONE, 2016
The aim of this study was to identify new genetic variants associated with the severity of ankylosing spondylitis (AS). We sequenced the exome of eight patients diagnosed with AS, selected on the basis of the severity of their clinical parameters.
Jose Ramón Vidal-Castiñeira, Antonio López-Vázquez, Roberto Diaz-Peña, Paula Diaz-Bulnes, Pablo Martinez-Camblor, Eliecer Coto, Pablo Coto-Segura, Jacome Bruges-Armas, Jose Antonio Pinto, Francisco Jose Blanco, Alejandra Sánchez, Juan Mulero, Ruben Queiro, Carlos Lopez-Larrea   +13 more
doaj   +9 more sources

Moving instead of asking? Performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis [PDF]

Arthritis Research & Therapy, 2012
Abstract Introduction Ankylosing Spondylitis (AS) is characterised by limitations in physical function. The Bath Ankylosing Spondylitis Functional Index (BASFI) is considered to be the gold-standard to assess physical function in AS patients.
van Weely, S.F.E., van Denderen, J.C., Steultjens, M.P., van der Leeden, M., Nurmohamed, M.T., Dekker, J., Dijkmans, B.A.C., van der Horst-Bruinsma, I.E.   +7 more
openaire   +8 more sources

Both baseline clinical factors and genetic polymorphisms influence the development of severe functional status in ankylosing spondylitis. [PDF]

PLoS ONE, 2012
Functional severity in ankylosing spondylitis (AS) patients is variable and difficult to predict early. The aim of our study was to assess whether a combination of baseline clinical factors and genetic markers may predict the development of severe ...
Ruxandra Schiotis, Nerea Bartolomé, Alejandra Sánchez, Magdalena Szczypiorska, Jesús Sanz, Eduardo Cuende, Eduardo Collantes Estevez, Antonio Martínez, Diego Tejedor, Marta Artieda, Anca Buzoianu, Juan Mulero   +11 more
doaj   +5 more sources

Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts [PDF]

, 2012
The availability of population-specific normative data regarding disease severity measures is essential for patient assessment. The goals of the current study were to characterize the pattern of ankylosing spondylitis (AS) in Portuguese patients and to develop reference centile charts for BASDAI, BASFI, BASMI and mSASSS, the most widely used assessment
M. Pimentel-Santos, F., Mourão, Ana Filipa, Ribeiro, Célia, Costa, J. A., Santos, Helena, Barcelos, A., Pinto, Patricia, Godinho, F., Cruz, Margarida, Vieira-Sousa, Elsa, Santos, Rui André, Rabiais, Sara, Félix, Jorge, Fonseca, J. E., Guedes-Pinto, Henrique, Brown, Matthew A., De Matos, A. A., Ribeiro, C., Bravo Pimentão, J., Mateus, M., Nero, P., Araújo, P., Falcão, S., Pinto, T. L., Castelão, W., Vieira De Sousa, E., Caetano-Lopes, J., Silva, C., Simões, E., Madeira, H., Vaz Patto, J., Ferreira, J., Micaelo, M., Mediavilla, M. J., Sousa, M., Soares Branco, P., Godinho, F., Canas Da Silva, J., Garcês, S., Tavares, V., Ribeiro, A., Araújo, D., Costa, J. A., Costa, L., Afonso, M. C., Bogas, M., Alcino, S., Pinto, P., Cravo, A. R., Sequeira, G., Santos, R. A., Barcelos, A., Cunha, I., Cruz, M.   +53 more
openaire   +4 more sources

The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study [PDF]

, 2012
INTRODUCTION: The aim of this study was to investigate the effect of three years of tumor necrosis factor-alpha (TNF-alpha) blocking therapy on bone turnover as well as to analyze the predictive value of early changes in bone turnover markers (BTM) for ...
Arends, S., Bos, R., Brouwer, E., Groen, H., Houtman, P.M., Kallenberg, C.G., Leijsma, M.K., Spoorenberg, A., van der Veer, E.   +8 more
core   +12 more sources

Assessment of functional disability and quality of life in patients with ankylosing spondylitis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2009
Introduction Ankylosing spondylitis is a chronic progressive autoimmune inflammatory disorder involving mainly the axial skeleton and larger peripheral joints that progressively limits spinal mobility and may lead to irreversible structural changes and ...
Mustur Dušan, Vesović-Potić Vladislava, Stanisavljević Dejana, Ille Tatjana, Ille Mihailo   +4 more
doaj   +1 more source

Efficacy and safety of ixekizumab through 52 weeks in two phase 3, randomised, controlled clinical trials in patients with active radiographic axial spondyloarthritis (COAST-V and COAST-W). [PDF]

, 2020
OBJECTIVES: To investigate the efficacy and safety of ixekizumab for up to 52 weeks in two phase 3 studies of patients with active radiographic axial spondyloarthritis (r-axSpA) who were biological disease-modifying antirheumatic drug (bDMARD)-naive ...
Baraliakos, X., Bertram, C.C., Bosch, F. van den, Carlier, H., COAST-V Study Grp, COAST-W Study Grp, Deodhar, A., Dougados, M., Ermann, J., Gallo, G., Gensler, L.S., Heijde, D. van der, Landewe, R., Li, X.Q., Maksymowych, W.P., Sieper, J., Tomita, T., Walsh, J.A., Wei, J.C.C., Zhao, F.Y.   +19 more
core   +3 more sources

Impact of disease outcomes on the Assessment of SpondyloArthritis International Society Health Index (ASAS HI): a Bayesian network analysis of the DESIR cohort

RMD Open, 2023
Objective The objective of this study is to build a structural model visualising and quantifying the interrelationships of different disease outcomes with the Assessment of SpondyloArthritis International Society Health Index (ASAS HI) in patients with ...
Sofia Ramiro, Robert Landewé, Désirée van der Heijde, Maxime Dougados, Annelies Boonen, Jürgen Braun, Uta Kiltz, Imke Redeker   +7 more
doaj   +1 more source

Back pain and functional status in patients with ankylosing spondylitis during pregnancy

Современная ревматология, 2019
Inflammatory rhythm back pain and enthesitis are one of the main clinical manifestations of ankylosing spondylitis (AS), which increase in severity during pregnancy.
O. A. Krichevskaya, Z. M. Gandaloeva, A. B. Demina, S. I. Glukhova, T. V. Dubinina   +4 more
doaj   +1 more source

Disease and psychological status in ankylosing spondylitis. [PDF]

, 2006
Objectives. Psychological factors may be important in the assessment and management of ankylosing spondylitis (AS). Our primary objective was to describe associations between disease and psychological status in AS, using AS-specific assessment tools and ...
Goodacre, J. A., Goodacre, L., Grennan, D., Martindale, J., Smith, J., Sutton, Chris J   +5 more
core   +1 more source