Results 61 to 70 of about 5,322 (214)

Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force [PDF]

, 2013
Background: Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just emerging for spondyloarthritis (SpA). Objective: To define the treatment
Baraliakos, Xenofon, Betteridge, Neil, Braun, Jürgen, Burgos-Vargas, Ruben, Collantes-Estevez, Eduardo, de Wit, Martinus, Deodhar, Atul, Dougados, Maxime, Elewaut, Dirk, Emery, Paul, FitzGerald, Oliver, Gossec, Laure, Helliwell, Philip, Jongkees, Merryn, Kavanaugh, Arthur, Kvien, Tore K, Landewé, Robert, Luger, Thomas, Maccarone, Mara, Mease, Philip, Olivieri, Ignazio, Redlich, Kurt, Reveille, John, Ritchlin, Christopher, Rudwaleit, Martin, Schoels, Monika, Sieper, Joachim, Smolen, Josef S, Van den Bosch, Filip, van der Heijde, Désirée, Wei, James Cheng-Chung, Winthrop, Kevin   +31 more
core   +2 more sources

Global Functioning in Axial Spondyloarthritis is Stronger Associated With Disease Activity and Function Than With Mobility and Radiographic Damage

Arthritis Care &Research, Volume 77, Issue 3, Page 385-392, March 2025.
Objective The Assessment of Spondyloarthritis International Society Health Index (ASAS HI) is a validated patient‐reported outcome (PRO) for global functioning of patients with axial spondyloarthritis (axSpA). The Epionics SPINE (ES) is an electronic device for assessment of axial mobility that provides an objective measure of spinal mobility by ...
David Kiefer, Jürgen Braun, Uta Kiltz, Varvara Chatzistefanidi, Daniela Adolf, Ilka Schwarze, Maria Kabelitz, Uwe Lange, Jan Brandt‐Jürgens, Edgar Stemmler, Sabine Sartingen, Xenofon Baraliakos   +11 more
wiley   +1 more source

Association Study of IL-12B Polymorphisms Susceptibility with Ankylosing Spondylitis in Mainland Han Population.

PLoS ONE, 2015
ObjectiveThis study aims to determine whether the genetic polymorphisms of IL-12B gene is a susceptibility factor to Ankylosing spondylitis (AS) in mainland Han Chinese population.MethodEight single-nucleotide polymorphisms (SNPs) (rs10045431, rs11167764,
Li Zhang, Dazhi Fan, Li Liu, Ting Yang, Ning Ding, Yanting Hu, Guoqi Cai, Li Wang, Lihong Xin, Qing Xia, Xiaona Li, Shengqian Xu, Jianhua Xu, Xiao Yang, Yanfeng Zou, Faming Pan   +15 more
doaj   +1 more source

Spondyloarthritis: Matrix Metalloproteinasesas Biomarkers of Pathogenesis and Response to Tumor Necrosis Factor (TNF) Inhibitors [PDF]

, 2017
The term spondyloarthritis (SpA) is used to describe a group of multifactorial chronic inflammatory diseases characterized by a predisposing genetic background and clinical manifestations typically involving the sacroiliac joint.
Ada Aita, Breban, Daniela Basso, Giovannini, Leonardo Punzi, Maksymowych, Mario Plebani, Massova, Parma, Roberta Ramonda, Stefania Moz, Woo   +11 more
core   +1 more source

Integration of Metabolomics and 16S Ribosomal RNA Sequencing to Elucidate the Pathogenesis of Ankylosing Spondylitis

Immunity, Inflammation and Disease, Volume 13, Issue 3, March 2025.
Disrupted gut microbiota and altered metabolites are present in AS patients. The analysis of microbiome and metabolomic data revealed significant differences between AS patients and HCs. ABSTRACT Objective Despite growing interest in the gut microbiota and blood metabolome in patients with ankylosing spondylitis (AS), its role remains poorly understood.
Xin Wang, Haojie Xu, Yuyan Chao, Chao Sun, Tingting Wang, Xiaoyun Fan, Lin Tang, Shengqian Xu, Changhao Xie   +8 more
wiley   +1 more source

Social role participation questionnaire for patients with ankylosing spondylitis: Translation into Dutch, reliability and construct validity [PDF]

, 2016
Objective: The Social Role Participation Questionnaire (SRPQ) assesses the influence of health on participation in 11 specific and one general participation role across 4 participation dimensions: 'importance', 'satisfaction with time', 'satisfaction ...
Arends, S. (Suzanne), Boonen, A. (Annelies), Gignac, M.A. (Monique), Heijde, D. (Desiree) van der, Heuft, L. (Liesbeth), Keszei, A.P. (András), Lacaille, D. (Diane), Landewé, R.B.M. (Robert), Luime, J.J. (Jolanda), Plasqui, G. (Guy), Spoorenberg, A. (A.), Van Gaalen, F. (Floris), Van Genderen, S. (Simon)   +12 more
core   +1 more source

A systematic review of sex and gender differences in treatment outcome of inflammatory skin diseases: Is it time for new guidelines?

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 3, Page 512-528, March 2025.
Abstract Background Gender‐ and sex‐specific differences in medicine were long‐time disregarded. Despite numerous indications of gender‐ and sex‐specific influences on the treatment of dermatological conditions, these have not yet been systematically investigated.
S. Preis, S. Ziehfreund, T. Biedermann, S. Horster, A. Zink   +4 more
wiley   +1 more source

Ankylosing spondylitis: how does it affect the quality of life?

Liječnički vjesnik, 2023
Ankylosing spondylitis is a progressive and debilitating disease known to immensely affect the quality of life and frequently cause disability. There are several instruments that measure this effect, such as Bath Ankylosing Spondylitis Disease Activity ...
Eva Perak, Valerija Plečko, Antonija Gračanin, Ana Gudelj Gračanin   +3 more
doaj   +1 more source

BioRePortAP, an electronic clinical record coupled with a database : an example of its use in a single [PDF]

, 2010
Aims: To evaluate the efficacy and safety of the treatment of psoriatic arthritis (PsA) patients with tumor necrosis factor (TNF) antagonists in the Rheumatology Department of Hospital de Santa Maria using the BioRePortAP.
Campanilho-Marques, R., Canhao, Helena, Costa, M., Fonseca, João Eurico, Martins, F., Pereira da Silva, José A., Polido-Pereira, J., Ramos, F., Rodrigues, A., Saavedra, M. J.   +9 more
core  

Efficacy and Safety of Intravenous Secukinumab in Patients With Active Axial Spondyloarthritis: Results From a Randomized, Placebo‐Controlled, Phase 3 Study

Arthritis &Rheumatology, Volume 77, Issue 2, Page 163-170, February 2025.
Objective Our goal was to assess the efficacy and safety of intravenous (IV) secukinumab for the treatment of adults with active axial spondyloarthritis (axSpA) in INVIGORATE‐1. Methods INVIGORATE‐1 (NCT04156620) was a randomized, double‐blind, parallel‐group, phase 3 trial in patients with active axSpA (either radiographic or nonradiographic ...
Atul Deodhar, Jerzy Supronik, Alan Kivitz, Guillermo Valenzuela, Karen Kapur, Susanne Rohrer, Eva Dokoupilová, Hanno B. Richards, Karel Pavelka   +8 more
wiley   +1 more source