Results 71 to 80 of about 8,546 (232)

Real‐World Insights From Türkiye: Biologic DMARDs Usage in Spondyloarthritis Patients With Chronic Kidney Disease

International Journal of Rheumatic Diseases, Volume 28, Issue 5, May 2025.
ABSTRACT Aim The objective was to evaluate biologic disease‐modifying antirheumatic drugs (DMARDs) and their side effects that hindered the continuation of treatment in a patient population diagnosed with spondyloarthritis (SpA) with a glomerular filtration rate (GFR) ≤ 60 mL/min, and to compare these side effects between patients with chronic kidney ...
Dilara Bulut Gökten, Mehmet Engin Tezcan, Burcu Yağız, Abdulsamet Erden, Gezmiş Kimyon, Nazife Şule Yaşar Bilge, Levent Kılıç, Belkıs Nihan Coşkun, Emine Duygu Ersözlü, Orhan Küçükşahin, Süleyman Serdar Koca, Emel Gönüllü, Muhammet Çınar, Servet Akar, Hakan Emmungil, Timuçin Kaşifoğlu, Cemal Bes, Aşkın Ateş, Yavuz Pehlivan, Sedat Kiraz, Ali İhsan Ertenli, Hüseyin Ediz Dalkılıç, Umut Kalyoncu, Rıdvan Mercan   +23 more
wiley   +1 more source

Global Functioning in Axial Spondyloarthritis is Stronger Associated With Disease Activity and Function Than With Mobility and Radiographic Damage

Arthritis Care &Research, Volume 77, Issue 3, Page 385-392, March 2025.
Objective The Assessment of Spondyloarthritis International Society Health Index (ASAS HI) is a validated patient‐reported outcome (PRO) for global functioning of patients with axial spondyloarthritis (axSpA). The Epionics SPINE (ES) is an electronic device for assessment of axial mobility that provides an objective measure of spinal mobility by ...
David Kiefer, Jürgen Braun, Uta Kiltz, Varvara Chatzistefanidi, Daniela Adolf, Ilka Schwarze, Maria Kabelitz, Uwe Lange, Jan Brandt‐Jürgens, Edgar Stemmler, Sabine Sartingen, Xenofon Baraliakos   +11 more
wiley   +1 more source

Integration of Metabolomics and 16S Ribosomal RNA Sequencing to Elucidate the Pathogenesis of Ankylosing Spondylitis

Immunity, Inflammation and Disease, Volume 13, Issue 3, March 2025.
Disrupted gut microbiota and altered metabolites are present in AS patients. The analysis of microbiome and metabolomic data revealed significant differences between AS patients and HCs. ABSTRACT Objective Despite growing interest in the gut microbiota and blood metabolome in patients with ankylosing spondylitis (AS), its role remains poorly understood.
Xin Wang, Haojie Xu, Yuyan Chao, Chao Sun, Tingting Wang, Xiaoyun Fan, Lin Tang, Shengqian Xu, Changhao Xie   +8 more
wiley   +1 more source

Disease Activity and Patient-Reported Health Measures in Relation to Cytokine Levels in Ankylosing Spondylitis

Rheumatology and Therapy, 2019
Introduction Ankylosing spondylitis (AS) is a lifelong condition where spinal inflammation causes chronic back pain and restriction of spinal function.
Johannes C. Nossent, Sylvia Sagen-Johnsen, Gunnstein Bakland   +2 more
doaj   +1 more source

A systematic review of sex and gender differences in treatment outcome of inflammatory skin diseases: Is it time for new guidelines?

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 3, Page 512-528, March 2025.
Abstract Background Gender‐ and sex‐specific differences in medicine were long‐time disregarded. Despite numerous indications of gender‐ and sex‐specific influences on the treatment of dermatological conditions, these have not yet been systematically investigated.
S. Preis, S. Ziehfreund, T. Biedermann, S. Horster, A. Zink   +4 more
wiley   +1 more source

A 3D assessment and feedback tool for Ankylosing Spondylitis from the perspective of healthcare professionals [PDF]

, 2016
To investigate the utility of 3D visualization technology to augment assessment and feedback for Ankylosing Spondylitis (AS), a visualization prototype was developed, and both subjective and objective measures of current assessment instruments were ...
Kay, S, Li, S, Porter, SB
core   +3 more sources

Efficacy and Safety of Intravenous Secukinumab in Patients With Active Axial Spondyloarthritis: Results From a Randomized, Placebo‐Controlled, Phase 3 Study

Arthritis &Rheumatology, Volume 77, Issue 2, Page 163-170, February 2025.
Objective Our goal was to assess the efficacy and safety of intravenous (IV) secukinumab for the treatment of adults with active axial spondyloarthritis (axSpA) in INVIGORATE‐1. Methods INVIGORATE‐1 (NCT04156620) was a randomized, double‐blind, parallel‐group, phase 3 trial in patients with active axSpA (either radiographic or nonradiographic ...
Atul Deodhar, Jerzy Supronik, Alan Kivitz, Guillermo Valenzuela, Karen Kapur, Susanne Rohrer, Eva Dokoupilová, Hanno B. Richards, Karel Pavelka   +8 more
wiley   +1 more source

When Usual Care Is Not So Usual: Protocol Violations and Generalizability in a Treat‐to‐Target Strategy Trial in Patients With Axial Spondyloarthritis

Arthritis Care &Research, Volume 76, Issue 11, Page 1540-1548, November 2024.
Objective The objective of this study was to evaluate the impact of protocol violations in the treat‐to‐target group in the Tight Control in Spondyloarthritis (TICOSPA) trial and to compare the proportion of patients optimally treated according to the Assessment of Spondyloarthritis International Society (ASAS)/EULAR 2016 recommendations for patients ...
Clementina López‐Medina, Filip van den Bosch, Désirée van der Heijde, Maxime Dougados, Anna Molto   +4 more
wiley   +1 more source

Non-Steroidal Anti-Inflammatory Drug Etoricoxib Facilitates the Application of Individualized Exercise Programs in Patients with Ankylosing Spondylitis

Medicina, 2020
Background and objectives: The main objective of this study is to highlight the efficiency of different therapeutic means in patients with ankylosing spondylitis, resulting in the improvement of their quality of life.
Iulia Rahela Marcu, Dalia Dop, Vlad Padureanu, Stefan Adrian Niculescu, Rodica Padureanu, Carmen Elena Niculescu, Otilia Constantina Rogoveanu   +6 more
doaj   +1 more source

DISEASE ACTIVITY INDICES AND C-REACTIVE PROTEIN PREDICT SWITCHING OF THE FIRST BIOLOGICAL AGENT IN ANKYLOSING SPONDYLITIS PATIENTS – A SINGLE-CENTER OBSERVATIONAL STUDY [PDF]

Romanian Journal of Rheumatology, 2017
Objective. The study aimed at observing drug survival and determining potential predictors of anti-TNFα switch among ankylosing spondylitis (AS) patients. Methods. The study retrospectively recorded clinical data of patients fulfilling modified New York
Marius Trandafir, Claudiu C. Popescu, Monica Gabriela Dimancescu, Florian Berghea, Violeta Bojinca, Denisa Predeteanu   +5 more
doaj   +1 more source