Results 171 to 180 of about 3,773,115 (336)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation (TAVI) [PDF]

, 2017
Aims This study aimed to assess functional course in elderly patients undergoing transcatheter aortic valve implantation (TAVI) and to find predictors of functional decline.
Bischoff, Seraina, Carrel, Thierry, Gandon, Marianne, Huber, Christoph, Jüni, Peter, Moser, André, Neumann, Stephanie, Schoenenberger, Andreas W., Schoenenberger, Christa-Maria, Stortecky, Stefan, Stuck, Andreas E., Wenaweser, Peter, Windecker, Stephan   +12 more
core  

Recognizing Activities of Daily Living from Egocentric Images [PDF]

arXiv, 2017
Recognizing Activities of Daily Living (ADLs) has a large number of health applications, such as characterize lifestyle for habit improvement, nursing and rehabilitation services. Wearable cameras can daily gather large amounts of image data that provide rich visual information about ADLs than using other wearable sensors. In this paper, we explore the
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Dependence in basic activities of daily living in elderly fallers and non-fallers

Kairós Gerontologia, 2015
The objective of this study was to identify the influence of level of functional dependence in basic activities of daily living in elderly fallers and non-fallers. 100 subjects were assessed, both genders, with a mean age 71,82 years.
Luciana Paludetti Zubieta Traldi, Jair Lício Ferreira Santos   +1 more
doaj  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Subjective Health as a Predictor of Physical Function in Older Women [PDF]

, 2020
Introduction: Globally, populations are ageing, which has increased the urgency of supporting health in older adults. Two key measures used to examine health in older populations are subjective health, a measure of global health, and physical function, a
Redekop, Rachel
core  

LSC-ADL: An Activity of Daily Living (ADL)-Annotated Lifelog Dataset Generated via Semi-Automatic Clustering [PDF]

arXiv
Lifelogging involves continuously capturing personal data through wearable cameras, providing an egocentric view of daily activities. Lifelog retrieval aims to search and retrieve relevant moments from this data, yet existing methods largely overlook activity-level annotations, which capture temporal relationships and enrich semantic understanding.
arxiv  

Recognizing Activities of Daily Living with a Wrist-mounted Camera [PDF]

arXiv, 2015
We present a novel dataset and a novel algorithm for recognizing activities of daily living (ADL) from a first-person wearable camera. Handled objects are crucially important for egocentric ADL recognition. For specific examination of objects related to users' actions separately from other objects in an environment, many previous works have addressed ...
arxiv  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source