Results 181 to 190 of about 3,773,115 (336)

Functional disability and its associated factors among community- dweller older adults living in Gondar Town, Ethiopia: a community-based cross-sectional study

BMC Public Health
Background Functional disability is an emerging public health concern that has an impact on the health and quality of life of older adults. If functional disability recognized early, it will be possible to support them to live independently.
Mihret Dejen Takele, Getachew Azeze Eriku, Destaw Marie Merawie, Fiseha Sefiwu Zinabu, Molla Fentanew, Gashaw Jember Belay, Alemu Kassaw Kibret   +6 more
doaj   +1 more source

Detecting Daily Living Gait Amid Huntington's Disease Chorea using a Foundation Deep Learning Model [PDF]

arXiv
Wearable sensors offer a non-invasive way to collect physical activity (PA) data, with walking as a key component. Existing models often struggle to detect gait bouts in individuals with neurodegenerative diseases (NDDs) involving involuntary movements.
arxiv  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Functional Status and Comorbidities in Older Patient Attending Outpatient in a Tertiary Care Hospital: An Observational Study

Journal of Nepal Medical Association
Introduction: With the increasing geriatric population, the demand of the geriatric care has been increasing worldwide. Numerous comorbidities like hypertension, COPD, diabetes mellitus, arthritis, are seen commonly in the older population of Nepal ...
Ananta Aryal, Anil Aryal, Rhijuta Pokharel, Shrinkhala Timsina, Shirjan Gautam, Saurav Jha, Subash Pant   +6 more
doaj   +1 more source

Generative Pretrained Embedding and Hierarchical Irregular Time Series Representation for Daily Living Activity Recognition [PDF]

Within the evolving landscape of smart homes, the precise recognition of daily living activities using ambient sensor data stands paramount. This paper not only aims to bolster existing algorithms by evaluating two distinct pretrained embeddings suited for ambient sensor activations but also introduces a novel hierarchical architecture.
arxiv   +1 more source

Identifying Human Indoor Daily Life Behavior employing Thermal Sensor Arrays (TSAs) [PDF]

arXiv
Daily activity monitoring systems used in households provide vital information for health status, particularly with aging residents. Multiple approaches have been introduced to achieve such goals, typically obtrusive and non-obtrusive. Amongst the obtrusive approaches are the wearable devices, and among the non-obtrusive approaches are the movement ...
arxiv  

DarkDNS: Revisiting the Value of Rapid Zone Update [PDF]

Malicious actors exploit the DNS namespace to launch spam campaigns, phishing attacks, malware, and other harmful activities. Combating these threats requires visibility into domain existence, ownership and nameservice activity that the DNS protocol does not itself provide.
arxiv   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Unmet need for assistance with activities of daily life among older adults in Brazil [PDF]

, 2018
OBJECTIVE: To estimate the proportion of unmet need for personal assistance for basic and instrumental activities of daily life and to evaluate socioeconomic inequalities related to the unmet need among community-dwelling Brazilian older adults. METHODS:
Andrade, Fabiola Bof de, Andrade, Tania Bof de   +1 more
core   +1 more source