Results 191 to 200 of about 1,150,444 (321)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Inappropriate prescription of drugs, adverse events and basic activities of daily living in elderly

open access: yesInternational Physical Medicine & Rehabilitation Journal, 2021
Fajreldines A   +6 more
openaire   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

Long-term evolution of limitations in basic and instrumental activities of daily living after stroke

open access: yes, 2022
Durant la phase chronique, un an après l'accident vasculaire cérébral (AVC), l'évolution des limitations des activités de la vie quotidienne (AVQ) et des activités instrumentales de la vie quotidienne (AIVQ) reste mal connue. Ces limitations semblent se stabiliser dans un premier temps avant d'augmenter progressivement.
openaire   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

Evaluation of basic and instrumental activities of daily life of elderly participants in groups living together [PDF]

open access: diamond, 2014
Isaiane da Silva Carvalho   +4 more
openalex   +1 more source

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