Results 61 to 70 of about 1,150,117 (291)
Racial Differences on Association of Depressive Symptoms With Combined Basic and Instrumental Activities of Daily Living [PDF]
Depressive symptoms are predictive of multiple degenerative diseases in older age adults. However, the association of depressive symptoms with onset and progression of disability have not been studied.In a cohort of community-dwelling, older black and white adults, 5,446 initially nondisabled subjects were followed annually for disability between 2000 ...
Kumar B, Rajan +4 more
openaire +2 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Background: The basic and instrumental activities of daily living are prerequisites for living with a good quality of life. On the contrary, lack of movement and physical inactivity are considered as the main cause of pressure injuries. Accordingly, this
Sahar Mohammadi +3 more
doaj
Background The influence of Body Mass Index (BMI) on the functional capacity for daily activities in older adults is a significant concern. Our study is designed to delineate the longitudinal relationship between BMI and the ability of daily living ...
Wang Lingying +6 more
doaj +1 more source
Mapping the neuroanatomy of functional decline in Alzheimer’s disease from basic to advanced activities of daily living [PDF]
Impairments in activities of daily living (ADL) are a criterion for Alzheimer's disease (AD) dementia. However, ADL gradually decline in AD, impacting on advanced (a-ADL, complex interpersonal or social functioning), instrumental (IADL, maintaining life in community), and finally basic functions (BADL, activities related to physiological and self ...
Slachevsky Chonchol, Andrea +12 more
openaire +4 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Disabilty in Older Adults with Depression [PDF]
Depression is a leading cause of disability among older adults which can change the scope of daily life for older adults and threaten their ability to live independently in the community.
Chisholm, Denise
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Background: Stroke incidence remains high in South Africa. Access to rehabilitation services is critical for stroke survivors to successfully reintegrate back into the community. This study aimed to explore the factors that influence stroke survivors'
Lizzy Mashapa +2 more
doaj +1 more source
(1) Background: It is important to evaluate the attention in the basic activities of daily life in the early hours of the day to evaluate the quality of care and to be able to increase the attention of human resources in case of observing an increase in ...
José Antonio Camacho-Conde +1 more
doaj +1 more source

