Results 31 to 40 of about 6,838,913 (224)

Numerical Model Updating and Validation of a Truss Railway Bridge considering Train-Track-Bridge Interaction Dynamics

open access: yesShock and Vibration
Vibration-based structural health monitoring (SHM) is crucial in assessing the integrity of large civil infrastructures. Developing an accurate finite element (FE) model that effectively reflects the dynamics of a full-scale structure is essential for ...
Mohammad Sadegh Ayubirad   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The effect of post-exercise rating time on session RPE [PDF]

open access: yes, 2012
This study evaluated the effect of post-exercise time on session rating of perceived exertion (sRPE) following steady-state and interval exercise bouts on a cycle ergometer.
Christen, Joshua D.
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Experimental determination of dynamic allowance for traffic loading in bridges [PDF]

open access: yes, 2012
Transportation Research Board 89th Annual Meeting, Washington DC, 2010-1-10 to 2010-1-14Bridge codes adopt values for dynamic allowance in traffic load models that are necessarily conservative to cover for an entire range of bridges with different ...
Dowling, Jason   +3 more
core   +1 more source

Application Characteristic Analysis of Spherical Roller Bearing in Industrial Gearbox

open access: yesJixie chuandong, 2016
The spherical roller bearings are widely applied in industrial gearbox,therefore the research of the running character of spherical roller bearings in gearbox is important for the designer.
Zhuo Fuhai
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Risk analysis of wind farm connection to existing grids using dynamic line rating

open access: yes, 2018
Dynamic Line Rating (DLR) is a technology that allows extending capacity of existing power lines for transportation higher electrical power capacity from production site to the customer.
Morozovska, Kateryna,   +5 more
core   +1 more source

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